Evidence map›Paper›PMID 34884836›Full record

ArticleInternational journal of molecular sciences2021

Zfhx3 Transcription Factor Represses the Expression of

Marcos Rubio-Alarcón, Anabel Cámara-Checa, María Dago, Teresa Crespo-García, Paloma Nieto-Marín, María Marín, José Luis Merino, Jorge Toquero, Rafael Salguero-Bodes, Juan Tamargo and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. New Insights into Cardiac Ion Channel Regulation 2.0.International journal of molecular sciences · 2023
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marcos Rubio-AlarcónDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Gregorio Marañón, CIBERCV, 28040 Madrid, Spain.
Anabel Cámara-ChecaDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Gregorio Marañón, CIBERCV, 28040 Madrid, Spain.
María DagoDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Gregorio Marañón, CIBERCV, 28040 Madrid, Spain.
Teresa Crespo-GarcíaDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Gregorio Marañón, CIBERCV, 28040 Madrid, Spain.ORCID 0000-0003-3635-1446
Paloma Nieto-MarínDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Gregorio Marañón, CIBERCV, 28040 Madrid, Spain.
María MarínDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Gregorio Marañón, CIBERCV, 28040 Madrid, Spain.
José Luis MerinoDepartment of Cardiology, Hospital Universitario La Paz, Instituto de Investigación Sanitaria la Paz, CIBERCV, 28046 Madrid, Spain.ORCID 0000-0002-1737-1903
Jorge ToqueroDepartment of Cardiology, Hospital Universitario Puerta de Hierro, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, CIBERCV, Majadahonda, 28222 Madrid, Spain.
Rafael Salguero-BodesDepartment of Cardiology, Hospital Universitario 12 de Octubre, Instituto de Investigación Hospital 12 de Octubre, CIBERCV, 28041 Madrid, Spain.ORCID 0000-0003-1038-9710
Juan TamargoDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Gregorio Marañón, CIBERCV, 28040 Madrid, Spain.
Jorge CebriánDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Gregorio Marañón, CIBERCV, 28040 Madrid, Spain.ORCID 0000-0001-5070-0070
Eva DelpónDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Gregorio Marañón, CIBERCV, 28040 Madrid, Spain.ORCID 0000-0003-4499-8645
Ricardo CaballeroDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Gregorio Marañón, CIBERCV, 28040 Madrid, Spain.

Funding

Comunidad de Madrid 2018-72/BMD-10724Comunidad de Madrid S2017/BMD-3738Instituto de Salud Carlos III CB16/11/00303Ministry of Economy, Industry and Competitiveness SAF2017-88116-P
6 · The paper itself

Abstract

The

Indexed as

AdultBrugada SyndromeCell LineFemaleGene Expression RegulationHomeodomain ProteinsHumansMaleMembrane PotentialsMutation, MissenseMyocytes, CardiacNAV1.5 Voltage-Gated Sodium ChannelNedd4 Ubiquitin Protein LigasesPedigreeRNA InterferenceRNA, Small InterferingHomeodomain ProteinsNAV1.5 Voltage-Gated Sodium ChannelNedd4L protein, humanNedd4 Ubiquitin Protein LigasesRNA, Small InterferingSCN5A protein, humanT-Box Domain ProteinsT-box transcription factor 5ZFHX3 protein, humancardiacNav1.5patch-clampPitx2cSCN5Asodium currentTbx5Zfhx3

Identifiers

PMID34884836
PMCPMC8657907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.