Evidence map›Paper›PMID 34884796›Full record

ArticleInternational journal of molecular sciences2021

Skeletal Ryanodine Receptors Are Involved in Impaired Myogenic Differentiation in Duchenne Muscular Dystrophy Patients.

Pierre Meyer, Cécile Notarnicola, Albano C Meli, Stefan Matecki, Gérald Hugon, Jérémy Salvador, Mirna Khalil, Léonard Féasson, Claude Cances, Jérôme Cottalorda and 7 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. The two faces of mitochondrial CaJournal of physiology and biochemistry · 2026
    Review
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  9. Mitochondrial stress response and myogenic differentiation.Frontiers in cell and developmental biology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Pierre MeyerPhyMedExp, University of Montpellier, Inserm, CNRS, 34295 Montpellier, France.ORCID 0000-0001-5710-7376
Cécile NotarnicolaPhyMedExp, University of Montpellier, Inserm, CNRS, 34295 Montpellier, France.ORCID 0000-0001-8363-1614
Albano C MeliPhyMedExp, University of Montpellier, Inserm, CNRS, 34295 Montpellier, France.ORCID 0000-0002-1727-3027
Stefan MateckiPhyMedExp, University of Montpellier, Inserm, CNRS, 34295 Montpellier, France.
Gérald HugonPhyMedExp, University of Montpellier, Inserm, CNRS, 34295 Montpellier, France.ORCID 0000-0003-0772-6173
Jérémy SalvadorPhyMedExp, University of Montpellier, Inserm, CNRS, 34295 Montpellier, France.
Mirna KhalilClinical Investigation Center, Montpellier University Hospital, 34000 Montpellier, France.
Léonard FéassonMyology Unit, Reference Center for Neuromuscular Diseases Euro-NmD, Inter-University Laboratory of Human Movement Sciences-EA7424, University Hospital of Saint-Etienne, 42055 Saint-Etienne, France.ORCID 0000-0002-8163-5539
Claude CancesReference Center for Neuromuscular Diseases AOC, Pediatric Neurology Department, Toulouse University Hospital, 3100 Toulouse, France.
Jérôme CottalordaPediatric Orthopedic and Plastic Surgery Department, Montpellier University Hospital, 34295 Montpellier, France.
Isabelle DesguerreReference Center for Neuromuscular Diseases Paris Nord-Ile-de-France-Est, Pediatric Neurology Department, Necker Enfant Malades University Hospital, Assistance Publique des Hôpitaux de Paris Centre, Paris University, 75019 Paris, France.
Jean-Marie CuissetReference Center for Neuromuscular Diseases Nord-Ile-de-France-Est, Pediatric Neurology Department, Lille University Hospital, 59000 Lille, France.
Pascal SabouraudReference Center for Neuromuscular Diseases Nord-Ile-de-France-Est, Pediatric Neurology Department, Reims University Hospital, 51100 Reims, France.
Alain LacampagnePhyMedExp, University of Montpellier, Inserm, CNRS, 34295 Montpellier, France.ORCID 0000-0003-0264-1787
Hugues ChevassusClinical Investigation Center, Montpellier University Hospital, 34000 Montpellier, France.ORCID 0000-0001-8145-671X
François RivierPhyMedExp, University of Montpellier, Inserm, CNRS, 34295 Montpellier, France.
Gilles CarnacPhyMedExp, University of Montpellier, Inserm, CNRS, 34295 Montpellier, France.
Centre National de la Recherche Scientifique · FRUniversité de Montpellier · FRCentre Hospitalier Universitaire de Reims · FRCentre Hospitalier Universitaire de Saint-Étienne · FRHôpital Necker-Enfants Malades · FRUniversité Fédérale de Toulouse Midi-Pyrénées · FRUniversité Lille Nord de France · FR

Funding

Direction Générale de l'Offre de Soins - Institut National de la Santé et de la Recherche Médicale (DGOS-INSERM), France 2012-A00437-36
6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is characterized by progressive muscle wasting following repeated muscle damage and inadequate regeneration. Impaired myogenesis and differentiation play a major role in DMD as well as intracellular calcium (Ca

Indexed as

CalciumCalcium SignalingCell DifferentiationCells, CulturedChildChild, PreschoolDystrophinHumansMaleMuscle DevelopmentMuscle Fibers, SkeletalMuscle, SkeletalMuscular Dystrophy, DuchenneMyoblastsRyanodine Receptor Calcium Release ChannelSarcoplasmic ReticulumCalciumDystrophinFKBP1A protein, humanRyanodine Receptor Calcium Release ChannelRYR1 protein, humanTacrolimus Binding ProteinsDuchenne muscular dystrophyendomysial fibrosishumanmyogenesisryanodine receptor

Identifiers

PMID34884796
PMCPMC8657486
OpenAlexW3217514432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.