ReviewInternational journal of molecular sciences2021
Sex Bias in Differentiated Thyroid Cancer.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 102 citations in OpenAlex.
- Editorial Comment: Sex as a Prognostic Factor in Follicular Thyroid Carcinoma: An Answer That Depends on Age.Annals of surgical oncology · 2026Article
- Article
- Review
- Trends and disparities in thyroid cancer related mortality from 1999 to 2023: a CDC WONDER database analysis.BMC endocrine disorders · 2026Article
- Age Modifies the Prognostic Impact of Sex in Follicular Thyroid Carcinoma: A SEER Database Analysis.Annals of surgical oncology · 2026Article
- Personalized prognosis: construction and validation of a survival prediction model for older postoperative differentiated thyroid cancer patients.BMC geriatrics · 2026Article
- ANGPT2 Drives Thyroid Cancer Progression Through PI3K/AKT Signaling and Correlates With Poor Prognosis and Immune Infiltration.World journal of otorhinolaryngology - head and neck surgery · 2026Article
- Integrating Ultrasound and Clinicopathologic Characteristics to Predict the Invasive Papillary Thyroid Carcinoma Among Indeterminate Thyroid Nodules.Cancer management and research · 2026Article
- Cross-sectional analysis of 152 hyperthyroid cats presented for radioactive iodine therapy in South Korea.Frontiers in veterinary science · 2026Article
- Assessment of thyroid hormone profiles and derived ratios for predicting thyroid nodule malignancy using the Bethesda system: thyroid hormone ratios in malignancy risk stratification of thyroid nodules: a cross-sectional study.Sao Paulo medical journal = Revista paulista de medicina · 2026Article
- Patient age at diagnosis and biological sex in association with postoperative outcomes of thyroidectomy for low-risk papillary thyroid cancer in the U.S. Military Health System.Gland surgery · 2025Article
- Psychological distress and sleep in papillary thyroid carcinoma: a case-control study.BMC psychiatry · 2025Article
- RASGEF1C methylation for the distinguishment and classification of benign and malignant thyroid tumors.Clinical epigenetics · 2025Article
- Thyroid Cancer: Epidemiology, Classification, Risk Factors, Diagnostic and Prognostic Markers, and Current Treatment Strategies.International journal of molecular sciences · 2025Review
- A spatially resolved transcriptome landscape during thyroid cancer progression.Cell reports. Medicine · 2025Article
- Thyroid Cancer Staging: Historical Evolution and Analysis From Macrocarcinoma to Microcarcinoma.Cureus · 2025Review
- Development and validation of a multidimensional machine learning-based nomogram for predicting central lymph node metastasis in papillary thyroid microcarcinoma.Gland surgery · 2025Article
- Relationship of modifiable risk factors with the incidence of thyroid cancer: a worldwide study.BMC research notes · 2025Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Differentiated thyroid cancers are more frequent in women than in men. These different frequencies may depend on differences in patient's behavior and in thyroid investigations. However, an impact on sexual hormones is likely, although this has been insufficiently elucidated. Estrogens may increase the production of mutagenic molecules in the thyroid cell and favor the proliferation and invasion of tumoral cells by regulating both the thyrocyte enzymatic machinery and the inflammatory process associated with tumor growth. On the other hand, the worse prognosis of thyroid cancer associated with the male gender is poorly explained.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.