Evidence map›Paper›PMID 34884695›Full record

ReviewInternational journal of molecular sciences2021

Antimicrobial Resistance and Inorganic Nanoparticles.

Andrea-Sarahí Balderrama-González, Hilda-Amelia Piñón-Castillo, Claudia-Adriana Ramírez-Valdespino, Linda-Lucila Landeros-Martínez, Erasmo Orrantia-Borunda, Hilda-Esperanza Esparza-Ponce

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. ZnO@TiOMaterials (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Green Synthesis of Silver Oxide Nanoparticles fromNanomaterials (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea-Sarahí Balderrama-GonzálezCentro de Investigación en Materiales Avanzados, S. C. Miguel de Cervantes 120, Complejo Industrial Chihuahua, Chihuahua 31136, Mexico.
Hilda-Amelia Piñón-CastilloFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua 31125, Mexico.ORCID 0000-0003-4454-8935
Claudia-Adriana Ramírez-ValdespinoCentro de Investigación en Materiales Avanzados, S. C. Miguel de Cervantes 120, Complejo Industrial Chihuahua, Chihuahua 31136, Mexico.ORCID 0000-0002-7772-060X
Linda-Lucila Landeros-MartínezFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua 31125, Mexico.ORCID 0000-0002-7240-1458
Erasmo Orrantia-BorundaCentro de Investigación en Materiales Avanzados, S. C. Miguel de Cervantes 120, Complejo Industrial Chihuahua, Chihuahua 31136, Mexico.
Hilda-Esperanza Esparza-PonceCentro de Investigación en Materiales Avanzados, S. C. Miguel de Cervantes 120, Complejo Industrial Chihuahua, Chihuahua 31136, Mexico.ORCID 0000-0001-9720-9588

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics are being less effective, which leads to high mortality in patients with infections and a high cost for the recovery of health, and the projections that are had for the future are not very encouraging which has led to consider antimicrobial resistance as a global health problem and to be the object of study by researchers. Although resistance to antibiotics occurs naturally, its appearance and spread have been increasing rapidly due to the inappropriate use of antibiotics in recent decades. A bacterium becomes resistant due to the transfer of genes encoding antibiotic resistance. Bacteria constantly mutate; therefore, their defense mechanisms mutate, as well. Nanotechnology plays a key role in antimicrobial resistance due to materials modified at the nanometer scale, allowing large numbers of molecules to assemble to have a dynamic interface. These nanomaterials act as carriers, and their design is mainly focused on introducing the temporal and spatial release of the payload of antibiotics. In addition, they generate new antimicrobial modalities for the bacteria, which are not capable of protecting themselves. So, nanoparticles are an adjunct mechanism to improve drug potency by reducing overall antibiotic exposure. These nanostructures can overcome cell barriers and deliver antibiotics to the cytoplasm to inhibit bacteria. This work aims to give a general vision between the antibiotics, the nanoparticles used as carriers, bacteria resistance, and the possible mechanisms that occur between them.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsBacteriaBacterial InfectionsDrug CarriersHumansInorganic ChemicalsNanoparticlesAnti-Bacterial AgentsDrug CarriersInorganic Chemicalsantimicrobial resistancebacteriananoparticlesresistance mechanism

Identifiers

PMID34884695
PMCPMC8657868

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.