Evidence map›Paper›PMID 34884649›Full record

ArticleInternational journal of molecular sciences2021

Reduced

Jenna Kitz, Cory Lefebvre, Joselia Carlos, Lori E Lowes, Alison L Allan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jenna KitzLondon Regional Cancer Program, London Health Sciences Centre, Department of Anatomy & Cell Biology, Western University, London, ON N6A 5W9, Canada.
Cory LefebvreLondon Regional Cancer Program, London Health Sciences Centre, Department of Anatomy & Cell Biology, Western University, London, ON N6A 5W9, Canada.
Joselia CarlosDepartment of Medical Biophysics, Western University, London, ON N6A 5C1, Canada.ORCID 0000-0002-4016-9500
Lori E LowesFlow Cytometry, London Health Sciences Centre, London, ON N6A 5W9, Canada.
Alison L AllanLondon Regional Cancer Program, London Health Sciences Centre, Department of Anatomy & Cell Biology, Western University, London, ON N6A 5W9, Canada.
Western University · CALondon Health Sciences Centre · CA

Funding

London Regional Cancer Program Catalyst GrantProstate Cancer Canada D2017-1974
6 · The paper itself

Abstract

Prostate cancer is the most common cancer in American men and the second leading cause of cancer-related death. Most of these deaths are associated with metastasis, a process involving the epithelial-to-mesenchymal (EMT) transition. Furthermore, growing evidence suggests that partial-EMT (p-EMT) may lead to more aggressive disease than complete EMT. In this study, the EMT-inducing transcription factor

Indexed as

DNA MethylationAntimetabolites, AntineoplasticAzacitidineBiomarkers, TumorCell Line, TumorCell MovementConnectinEpithelial-Mesenchymal TransitionHumansMalePC-3 CellsProstatic NeoplasmsZinc Finger E-box-Binding Homeobox 1Antimetabolites, AntineoplasticAzacitidineBiomarkers, TumorConnectinMYOM2 protein, humanZEB1 protein, humanZinc Finger E-box-Binding Homeobox 15-azacytidineDNA methylationepithelial-to-mesenchymal transition (EMT)metastasispartial-EMT (p-EMT)prostate cancerZeb1

Identifiers

PMID34884649
PMCPMC8657557
OpenAlexW3215684677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.