Evidence map›Paper›PMID 34884576›Full record

ArticleInternational journal of molecular sciences2021

Myelinosome Organelles in the Retina of R6/1 Huntington Disease (HD) Mice: Ubiquitous Distribution and Possible Role in Disease Spreading.

Marina G Yefimova, Emile Béré, Anne Cantereau-Becq, Annie-Claire Meunier-Balandre, Bruno Merceron, Agnès Burel, Karine Merienne, Célia Ravel, Frédéric Becq, Nicolas Bourmeyster

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Impact of Endocrine Disruptors upon Non-Genetic Inheritance.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Marina G YefimovaLaboratoire Signalisation et Transports Ioniques Membranaires, Université de Poitiers/CNRS, 1 Rue Georges Bonnet, 86022 Poitiers, France.ORCID 0000-0001-9036-4489
Emile BéréPlateforme IMAGE-UP, 1 Rue Georges Bonnet, 86022 Poitiers, France.
Anne Cantereau-BecqLaboratoire Signalisation et Transports Ioniques Membranaires, Université de Poitiers/CNRS, 1 Rue Georges Bonnet, 86022 Poitiers, France.ORCID 0000-0001-6372-4346
Annie-Claire Meunier-BalandreLaboratoire Signalisation et Transports Ioniques Membranaires, Université de Poitiers/CNRS, 1 Rue Georges Bonnet, 86022 Poitiers, France.
Bruno MerceronPlateforme IMAGE-UP, 1 Rue Georges Bonnet, 86022 Poitiers, France.
Agnès BurelPlateforme Mric TEM, BIOSIT UMS 34 80, Université de Rennes 1, 2 Av. Pr. Léon Bernard, CEDEX, 35043 Rennes, France.
Karine MerienneLaboratory of Cognitive and Adaptive Neurosciences (LNCA), University of Strasbourg, 67000 Strasbourg, France.
Célia RavelLaboratoire de Biologie de la Reproduction-CECOS, Hopital SUD, 16 Bd de Bulgarie, CEDEX, 35000 Rennes, France.
Frédéric BecqLaboratoire Signalisation et Transports Ioniques Membranaires, Université de Poitiers/CNRS, 1 Rue Georges Bonnet, 86022 Poitiers, France.
Nicolas BourmeysterLaboratoire Signalisation et Transports Ioniques Membranaires, Université de Poitiers/CNRS, 1 Rue Georges Bonnet, 86022 Poitiers, France.ORCID 0000-0002-9563-5142
Centre National de la Recherche Scientifique · FRHôpital Nord · FRUniversité de Rennes · FR

Funding

Agence Nationale de la Recherche ANR-2017-CE12-0027.
6 · The paper itself

Abstract

Visual deficit is one of the complications of Huntington disease (HD), a fatal neurological disorder caused by CAG trinucleotide expansions in the

Indexed as

AnimalsHumansHuntingtin ProteinHuntington DiseaseMiceMice, TransgenicMyelin SheathNeurogliaNeuronsOrganellesRetinaHTT protein, humanHuntingtin ProteinCAG expansionglial Müller cellsHuntington diseaseHuntington disease biomarkerHuntington disease spreadingmembrane fusionmutant Huntingtinmyelinosomesneurodegenerationretina

Identifiers

PMID34884576
PMCPMC8657466
OpenAlexW3217258633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.