Evidence map›Paper›PMID 34884531›Full record

ArticleInternational journal of molecular sciences2021

Tuning Physicochemical Properties of a Macroporous Polysaccharide-Based Scaffold for 3D Neuronal Culture.

Gaspard Gerschenfeld, Rachida Aid, Teresa Simon-Yarza, Soraya Lanouar, Patrick Charnay, Didier Letourneur, Piotr Topilko

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gaspard GerschenfeldEcole Normale Supérieure, PSL Research University, CNRS, Inserm, Institut de Biologie de l'Ecole Normale Supérieure (IBENS), F-75005 Paris, France.ORCID 0000-0002-2456-704X
Rachida AidINSERM U1148, LVTS, Université de Paris, X Bichat Hospital, 46 Rue H Huchard, F-75018 Paris, France.
Teresa Simon-YarzaINSERM U1148, LVTS, Université de Paris, X Bichat Hospital, 46 Rue H Huchard, F-75018 Paris, France.
Soraya LanouarINSERM U1148, LVTS, Université de Paris, X Bichat Hospital, 46 Rue H Huchard, F-75018 Paris, France.
Patrick CharnayEcole Normale Supérieure, PSL Research University, CNRS, Inserm, Institut de Biologie de l'Ecole Normale Supérieure (IBENS), F-75005 Paris, France.
Didier LetourneurINSERM U1148, LVTS, Université de Paris, X Bichat Hospital, 46 Rue H Huchard, F-75018 Paris, France.ORCID 0000-0003-2197-9468
Piotr TopilkoEcole Normale Supérieure, PSL Research University, CNRS, Inserm, Institut de Biologie de l'Ecole Normale Supérieure (IBENS), F-75005 Paris, France.ORCID 0000-0001-7381-6770
Inserm · FRCentre National de la Recherche Scientifique · FR

Funding

Agence Nationale de la Recherche ANR-10-LABX-54 MEMOLIFEAgence Nationale de la Recherche ANR-11- 386 IDEX-0001-02 PSL*
6 · The paper itself

Abstract

Central nervous system (CNS) lesions are a leading cause of death and disability worldwide. Three-dimensional neural cultures in biomaterials offer more physiologically relevant models for disease studies, toxicity screenings or in vivo transplantations. Herein, we describe the development and use of pullulan/dextran polysaccharide-based scaffolds for 3D neuronal culture. We first assessed scaffolding properties upon variation of the concentration (1%, 1.5%, 3%

Indexed as

AnimalsBiocompatible MaterialsCell AdhesionCell Culture Techniques, Three DimensionalCell SurvivalEmbryo, MammalianMiceMice, Inbred C57BLMice, Inbred DBANeuronsPolysaccharidesPorosityTissue EngineeringTissue ScaffoldsBiocompatible MaterialsPolysaccharidesembryonic neuronspolysaccharideporous scaffoldpullulan–dextran

Identifiers

PMID34884531
PMCPMC8657966
OpenAlexW3215316251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.