Evidence map›Paper›PMID 34884506›Full record

ArticleInternational journal of molecular sciences2021

Silver Nanoparticles Impair Cognitive Functions and Modify the Hippocampal Level of Neurotransmitters in a Coating-Dependent Manner.

Katarzyna Dziendzikowska, Małgorzata Węsierska, Joanna Gromadzka-Ostrowska, Jacek Wilczak, Michał Oczkowski, Sylwia Męczyńska-Wielgosz, Marcin Kruszewski

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Advance in Neurotoxicity Research from Development to Aging.International journal of molecular sciences · 2023
    Article
  9. The effect of silver nanoparticles on learning and memory in rodents: "a systematic review".Journal of occupational medicine and toxicology (London, England) · 2023
    Review
  10. Article
  11. Article
  12. Biomimetic nanoparticles for tumor immunotherapy.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Katarzyna DziendzikowskaChair of Nutrition Physiology, Department of Dietetics, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159C, 02-776 Warsaw, Poland.ORCID 0000-0002-8069-6356
Małgorzata WęsierskaLaboratory of Neurophysiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.
Joanna Gromadzka-OstrowskaChair of Nutrition Physiology, Department of Dietetics, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159C, 02-776 Warsaw, Poland.ORCID 0000-0002-9529-3744
Jacek WilczakDepartment of Physiological Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 159, 02-776 Warsaw, Poland.ORCID 0000-0002-3053-3663
Michał OczkowskiChair of Nutrition Physiology, Department of Dietetics, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159C, 02-776 Warsaw, Poland.ORCID 0000-0002-5999-5140
Sylwia Męczyńska-WielgoszCentre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.ORCID 0000-0002-9475-983X
Marcin KruszewskiCentre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.ORCID 0000-0003-4554-8566
Warsaw University of Life Sciences · PLInstytut Chemii i Techniki Jądrowej · PLInstytut Biologii Doświadczalnej im. Marcelego Nenckiego · PL

Funding

National Science Centre, Poland MINIATURA I, 2017/01/X/NZ7/00648
6 · The paper itself

Abstract

Due to their potent antibacterial properties, silver nanoparticles (AgNPs) are widely used in industry and medicine. However, they can cross the brain-blood barrier, posing a risk to the brain and its functions. In our previous study, we demonstrated that oral administration of bovine serum albumin (BSA)-coated AgNPs caused an impairment in spatial memory in a dose-independent manner. In this study, we evaluated the effects of AgNPs coating material on cognition, spatial memory functioning, and neurotransmitter levels in rat hippocampus. AgNPs coated with BSA (AgNPs(BSA)), polyethylene glycol (AgNPs(PEG)), or citrate (AgNPs(Cit)) or silver ions (Ag

Indexed as

AnimalsCitratesCognition DisordersCytokinesHippocampusMaleMetal NanoparticlesPolyethylene GlycolsRatsRats, WistarSerum Albumin, BovineSilverCitratesCytokinesPolyethylene GlycolsSerum Albumin, BovineSilveractive allothetic place avoidance taskhippocampusinflammationnanoparticle coatingneurotransmitterssilver nanoparticlesspatial long- and short-term memory

Identifiers

PMID34884506
PMCPMC8657429
OpenAlexW3215890537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.