Evidence map›Paper›PMID 34884496›Full record

ReviewInternational journal of molecular sciences2021

Phytosterols in Seaweeds: An Overview on Biosynthesis to Biomedical Applications.

Soo-In Sohn, Periyasamy Rathinapriya, Sekaran Balaji, Devasahayam Jaya Balan, Thirukannamangai Krishnan Swetha, Ravindran Durgadevi, Selvaraj Alagulakshmi, Patchiappan Singaraj, Subramani Pandian

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. The Effect ofNutrients · 2024
    Trial
  2. Article
  3. Article
  4. Review
  5. From Sea to Sweet: Seaweed's Role in Nutritious and Sustainable Confectionery.Comprehensive reviews in food science and food safety · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. On the Antimicrobial Potential ofInternational journal of molecular sciences · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Oil Yield and Bioactive Compounds ofPlants (Basel, Switzerland) · 2025
    Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Soo-In SohnDepartment of Agricultural Biotechnology, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju 54874, Korea.ORCID 0000-0001-8819-7247
Periyasamy RathinapriyaDepartment of Biotechnology, Alagappa University, Karaikudi 630 003, India.ORCID 0000-0002-2888-7075
Sekaran BalajiIndependent Researcher, Madurai 625 020, India.
Devasahayam Jaya BalanDepartment of Biotechnology, Alagappa University, Karaikudi 630 003, India.
Thirukannamangai Krishnan SwethaDepartment of Biotechnology, Alagappa University, Karaikudi 630 003, India.
Ravindran DurgadeviDepartment of Biotechnology, Alagappa University, Karaikudi 630 003, India.
Selvaraj AlagulakshmiDepartment of Biotechnology, Alagappa University, Karaikudi 630 003, India.
Patchiappan SingarajIndependent Researcher, Madurai 625 020, India.
Subramani PandianDepartment of Agricultural Biotechnology, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju 54874, Korea.ORCID 0000-0002-1445-8122

Funding

Rural Development Administration Project No. PJ014929022021
6 · The paper itself

Abstract

Seaweed extracts are considered effective therapeutic alternatives to synthetic anticancer, antioxidant, and antimicrobial agents, owing to their availability, low cost, greater efficacy, eco-friendliness, and non-toxic nature. Since the bioactive constituents of seaweed, in particular, phytosterols, possess plenty of medicinal benefits over other conventional pharmaceutical agents, they have been extensively evaluated for many years. Fortunately, recent advances in phytosterol-based research have begun to unravel the evidence concerning these important processes and to endow the field with the understanding and identification of the potential contributions of seaweed-steroidal molecules that can be used as chemotherapeutic drugs. Despite the myriad of research interests in phytosterols, there is an immense need to fill the void with an up-to-date literature survey elucidating their biosynthesis, pharmacological effects, and other biomedical applications. Hence, in the present review, we summarize studies dealing with several types of seaweed to provide a comprehensive overview of the structural determination of several phytosterol molecules, their properties, biosynthetic pathways, and mechanisms of action, along with their health benefits, which could significantly contribute to the development of novel drugs and functional foods.

Indexed as

Functional FoodAnimalsAnti-Infective AgentsAntineoplastic AgentsAntioxidantsHumansPhytosterolsSeaweedAnti-Infective AgentsAntineoplastic AgentsAntioxidantsPhytosterolsantimicrobialsantioxidantsfunctional foodsphytosterolsseaweedsβ-sitosterol

Identifiers

PMID34884496
PMCPMC8657749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.