Evidence map›Paper›PMID 34884466›Full record

ReviewInternational journal of molecular sciences2021

Implications of Gut Microbiota in Complex Human Diseases.

Dahai Yu, Xin Meng, Willem M de Vos, Hao Wu, Xuexun Fang, Amit K Maiti

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The impact ofFrontiers in cellular and infection microbiology · 2025
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Exploring the Effect of GastrointestinalAnimals : an open access journal from MDPI · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Nutritional Interventions withInternational journal of molecular sciences · 2023
    Article
  17. Programming Factors of Neonatal Intestinal Dysbiosis as a Cause of Disease.International journal of molecular sciences · 2023
    Review
  18. Microbiota of the gastrointestinal tract: Friend or foe?World journal of gastroenterology · 2023
    Review
  19. Mediterranean Diet and Parkinson's Disease.International journal of molecular sciences · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dahai YuKey Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, 2699 Qianjin Street, Changchun 130012, China.ORCID 0000-0002-0594-5236
Xin MengKey Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, 2699 Qianjin Street, Changchun 130012, China.ORCID 0000-0003-0318-8363
Willem M de VosLaboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, The Netherlands.ORCID 0000-0002-0273-3166
Hao WuVascular Biology Program, Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Xuexun FangKey Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
Amit K MaitiDepartment of Genetics and Genomics, Mydnavar, 2645 Somerset Boulevard, Troy, MI 48084, USA.

Funding

Jilin Province Science and Technology Department YDZJ202101ZYTS080
6 · The paper itself

Abstract

Humans, throughout the life cycle, from birth to death, are accompanied by the presence of gut microbes. Environmental factors, lifestyle, age and other factors can affect the balance of intestinal microbiota and their impact on human health. A large amount of data show that dietary, prebiotics, antibiotics can regulate various diseases through gut microbes. In this review, we focus on the role of gut microbes in the development of metabolic, gastrointestinal, neurological, immune diseases and, cancer. We also discuss the interaction between gut microbes and the host with respect to their beneficial and harmful effects, including their metabolites, microbial enzymes, small molecules and inflammatory molecules. More specifically, we evaluate the potential ability of gut microbes to cure diseases through Fecal Microbial Transplantation (FMT), which is expected to become a new type of clinical strategy for the treatment of various diseases.

Indexed as

Anti-Bacterial AgentsDietDysbiosisFecal Microbiota TransplantationGastrointestinal MicrobiomeHumansPrebioticsProbioticsAnti-Bacterial AgentsPrebioticsbacteriadiseaseFMTgutmicrobiota

Identifiers

PMID34884466
PMCPMC8657718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.