Observational studyInternational journal of molecular sciences2021
Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph
Observational study in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 24 citations in OpenAlex.
- Early onset primary angle closure and foveal retinoschisis associated with a pseudo-homozygous CRB1 pathogenic variant.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- Metabolomic signatures suggest altered bile acid and energy metabolism in CRB1- retinopathies.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Novel Genotype-Phenotype Correlations inOphthalmology science · 2026Article
- Detailed Comparison Between Two Main Phenotypes of CRB1-Related Retinal Dystrophy, Pan-retinopathy and Maculopathy.Investigative ophthalmology & visual science · 2025Article
- The Specific Pathogenicity Pattern of the DifferentInternational journal of molecular sciences · 2025Article
- A Phenotypic Study of CRB1 Retinopathy Secondary to the Variant p.(Pro836Thr) Prevalent in Those of Black African Ancestry.Investigative ophthalmology & visual science · 2025Article
- Expanding the Clinical Spectrum ofInternational journal of molecular sciences · 2025Article
- Assessing Contrast Sensitivity Function in CRB1-Retinopathies: Exploring Child-Friendly Measures of Visual Function.Translational vision science & technology · 2024Article
- Human CRB1 and CRB2 form homo- and heteromeric protein complexes in the retina.Life science alliance · 2024Article
- Combining a prioritization strategy and functional studies nominates 5'UTR variants underlying inherited retinal disease.Genome medicine · 2024Article
- Characterization and AAV-mediatedMolecular therapy. Methods & clinical development · 2023Article
- CRB1-Associated Retinal Dystrophies: Genetics, Clinical Characteristics, and Natural History.American journal of ophthalmology · 2023Article
- Optical Coherence Tomography Angiography inJournal of clinical medicine · 2023Article
- Clinical and Therapeutic Evaluation of the Ten Most PrevalentBiomedicines · 2023Article
- Case report: Familial foveal retinoschisis caused byFrontiers in medicine · 2023Article
- Genetic dissection of non-syndromic retinitis pigmentosa.Indian journal of ophthalmology · 2022Review
- Biallelic Heterozygous Mutations in Crumbs Homolog-1 Gene Associated With Macular Retinoschisis and Angle-Closure Glaucoma: A Case Report and Literature Review.Frontiers in ophthalmology · 2022Article
- Retinitis Pigmentosa in the Puerto Rican Population: A Geographic Distribution.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 6 institutions in 1 country.
Kévin MairotDepartment of Ophthalmology, University North Hospital of Marseille, Sensgene Care Network, 13915 Marseille, France.ORCID 0000-0003-4280-9265
Vasily SmirnovDepartment of Visual Exploration and Neuro-Ophthalmology, Robert Salengro Hospital, Sensgene Care Network, 59045 Lille, France.
Béatrice BocquetNational Reference Centre for Inherited Sensory Diseases, University of Montpellier, Montpellier University Hospital, Sensgene Care Network, ERN-EYE Network, 34000 Montpellier, France.ORCID 0000-0002-6369-4818
Gilles LabesseStructural Biochemistry Centre, University of Montpellier, INSERM, CNRS, 34000 Montpellier, France.ORCID 0000-0002-6861-3300
Carl ArndtDepartment of Ophthalmology, Reims University Hospital, 51000 Reims, France.
Sabine Defoort-DhellemmesDepartment of Visual Exploration and Neuro-Ophthalmology, Robert Salengro Hospital, Sensgene Care Network, 59045 Lille, France.
Xavier ZanlonghiDepartment of Ophthalmology, Rennes University Hospital, 35000 Rennes, France.ORCID 0000-0003-4460-5346
Dalil HamrounDepartment of Research and Innovation, University of Montpellier, Montpellier University Hospital, 34000 Montpellier, France.ORCID 0000-0002-4853-8227
Danièle DenisDepartment of Ophthalmology, University North Hospital of Marseille, Sensgene Care Network, 13915 Marseille, France.
Marie-Christine PicotClinical Investigation Center (CIC), Clinical Research and Epidemiology Unit (URCE), University of Montpellier, 34000 Montpellier, France.
Thierry DavidDepartment of Ophthalmology, University North Hospital of Marseille, Sensgene Care Network, 13915 Marseille, France.ORCID 0000-0002-7192-1523
Olivier GrunewaldInserm, Lille University Hospital, U1172-LilNCog-Lille Neuroscience and Cognition, University of Lille, 59045 Lille, France.ORCID 0000-0002-9845-948X
Mako PégartNational Reference Centre for Inherited Sensory Diseases, University of Montpellier, Montpellier University Hospital, Sensgene Care Network, ERN-EYE Network, 34000 Montpellier, France.
Hélèna HuguetClinical Investigation Center (CIC), Clinical Research and Epidemiology Unit (URCE), University of Montpellier, 34000 Montpellier, France.
Anne-Françoise RouxInstitute for Neurosciences of Montpellier (INM), University of Montpellier, INSERM, 34000 Montpellier, France.ORCID 0000-0001-5914-2335
Vasiliki KalatzisInstitute for Neurosciences of Montpellier (INM), University of Montpellier, INSERM, 34000 Montpellier, France.ORCID 0000-0002-9626-8807
Claire-Marie DhaenensInserm, Lille University Hospital, U1172-LilNCog-Lille Neuroscience and Cognition, University of Lille, 59045 Lille, France.
Isabelle MeunierNational Reference Centre for Inherited Sensory Diseases, University of Montpellier, Montpellier University Hospital, Sensgene Care Network, ERN-EYE Network, 34000 Montpellier, France.
Inserm · FRUniversité de Montpellier · FRHôpital Roger Salengro · FRCentre Hospitalier Universitaire de Reims · FRCentre Hospitalier Universitaire de Rennes · FRCentre National de la Recherche Scientifique · FR
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pathogenic variants in
Indexed as
MutationAdolescentAge of OnsetAlternative SplicingChildChild, PreschoolEpendymoglial CellsEye ProteinsFemaleGenetic Association StudiesHumansInfantMacular DegenerationMaleMembrane ProteinsModels, MolecularCRB1 protein, humanEye ProteinsMembrane ProteinsNerve Tissue ProteinsCRB1early onset retinal dystrophyisoformsLeber congenital amaurosismacular dystrophyMüller cellspathogenic variantphotoreceptorsrod-cone dystrophyspectral domain optical coherence tomography
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.