Evidence map›Paper›PMID 34884440›Full record

ReviewInternational journal of molecular sciences2021

Natural Bioactive Molecules: An Alternative Approach to the Treatment and Control of COVID-19.

Fahadul Islam, Shabana Bibi, Atkia Farzana Khan Meem, Md Mohaimenul Islam, Md Saidur Rahaman, Sristy Bepary, Md Mizanur Rahman, Md Mominur Rahman, Amin Elzaki, Samih Kajoak and 5 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fahadul IslamDepartment of Pharmacy, Daffodil International University, Dhaka 1207, Bangladesh.ORCID 0000-0002-8167-8264
Shabana BibiYunnan Herbal Laboratory, College of Ecology and Environmental Sciences, Yunnan University, Kunming 650091, China.
Atkia Farzana Khan MeemDepartment of Pharmacy, Daffodil International University, Dhaka 1207, Bangladesh.
Md Mohaimenul IslamDepartment of Pharmacy, Daffodil International University, Dhaka 1207, Bangladesh.
Md Saidur RahamanDepartment of Pharmacy, Daffodil International University, Dhaka 1207, Bangladesh.ORCID 0000-0002-6634-3255
Sristy BeparyDepartment of Pharmacy, Daffodil International University, Dhaka 1207, Bangladesh.
Md Mizanur RahmanDepartment of Pharmacy, Daffodil International University, Dhaka 1207, Bangladesh.
Md Mominur RahmanDepartment of Pharmacy, Daffodil International University, Dhaka 1207, Bangladesh.ORCID 0000-0003-2357-283X
Amin ElzakiDepartment of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.ORCID 0000-0001-5277-1032
Samih KajoakDepartment of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.
Hamid OsmanDepartment of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.ORCID 0000-0001-5370-7358
Mohamed ElSamaniDepartment of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.
Mayeen Uddin KhandakerCentre for Applied Physics and Radiation Technologies, School of Engineering and Technology, Sunway University, Bandar Sunway 47500, Selangor, Malaysia.ORCID 0000-0003-3772-294X
Abubakr M IdrisDepartment of Chemistry, College of Science, King Khalid University, Abha 62529, Saudi Arabia.
Talha Bin EmranDepartment of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.ORCID 0000-0003-3188-2272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several coronaviruses (CoVs) have been associated with serious health hazards in recent decades, resulting in the deaths of thousands around the globe. The recent coronavirus pandemic has emphasized the importance of discovering novel and effective antiviral medicines as quickly as possible to prevent more loss of human lives. Positive-sense RNA viruses with group spikes protruding from their surfaces and an abnormally large RNA genome enclose CoVs. CoVs have already been related to a range of respiratory infectious diseases possibly fatal to humans, such as MERS, SARS, and the current COVID-19 outbreak. As a result, effective prevention, treatment, and medications against human coronavirus (HCoV) is urgently needed. In recent years, many natural substances have been discovered with a variety of biological significance, including antiviral properties. Throughout this work, we reviewed a wide range of natural substances that interrupt the life cycles for MERS and SARS, as well as their potential application in the treatment of COVID-19.

Indexed as

AlkaloidsAntiviral AgentsCOVID-19Disease OutbreaksFlavonoidsHumansMutationPandemicsSARS-CoV-2TerpenesAlkaloidsAntiviral AgentsFlavonoidsTerpenesalkaloidsbioactive moleculescoronavirusCOVID-19flavonoidsSARS-CoV-2terpenoids

Identifiers

PMID34884440
PMCPMC8658031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.