Evidence map›Paper›PMID 34884423›Full record

ArticleInternational journal of molecular sciences2021

Natural History of a Mouse Model Overexpressing the Dp71 Dystrophin Isoform.

Kenji Rowel Q Lim, Md Nur Ahad Shah, Stanley Woo, Harry Wilton-Clark, Pavel Zhabyeyev, Faqi Wang, Rika Maruyama, Gavin Y Oudit, Toshifumi Yokota

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kenji Rowel Q LimDepartment of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.ORCID 0000-0002-5484-4183
Md Nur Ahad ShahDepartment of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Stanley WooDepartment of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.ORCID 0000-0002-1661-3499
Harry Wilton-ClarkDepartment of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Pavel ZhabyeyevDepartment of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2G3, Canada.ORCID 0000-0003-0652-3235
Faqi WangDepartment of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2G3, Canada.
Rika MaruyamaDepartment of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.ORCID 0000-0002-5656-6930
Gavin Y OuditDepartment of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2G3, Canada.ORCID 0000-0002-9154-9028
Toshifumi YokotaDepartment of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
University of Alberta · CA

Funding

IMMUNIZATION AMONG DISTRICT OF COLUMBIA INFANTSZ01HD002115 · NICHD · CHILD HEALTH AND HUMAN DEVELOPMENT · PI SIMONS-MORTON, B · 1993 to 1996
–
Alberta Innovates Health Solutions FS G2019000283Canada Foundation for Innovation RES0045114Canada Research Chairs 950-232166CIHR PS 169193, FDN 143251, PJ51772Heart & Stroke Foundation 561422Women and Children's Health Research Institute IG 2115
6 · The paper itself

Abstract

Dystrophin is a 427 kDa protein that stabilizes muscle cell membranes through interactions with the cytoskeleton and various membrane-associated proteins. Loss of dystrophin as in Duchenne muscular dystrophy (DMD) causes progressive skeletal muscle weakness and cardiac dysfunction. Multiple promoters along the dystrophin gene (

Indexed as

AnimalsDisease Models, AnimalDystrophinHumansMiceMuscle, SkeletalMuscular Dystrophy, DuchenneMyocardiumPromoter Regions, GeneticProtein IsoformsDMD protein, humanDmd protein, mouseDystrophinProtein Isoformscardiac dysfunctiondel52Dp71Duchenne muscular dystrophydystrophic animal modeldystrophinhDMDdel52 miceWT mice

Identifiers

PMID34884423
PMCPMC8657860
OpenAlexW3217787228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.