ReviewJournal of clinical medicine2021
Biliary Atresia: Clinical Phenotypes and Aetiological Heterogeneity.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Rare spontaneous monochorionic dizygotic twins: a case report and a systematic review.BMC pregnancy and childbirth · 2022Pooled it
- Digital animation as a tool to enhance informed consent when recruiting infants with biliary atresia to a clinical trial.Journal of pediatric gastroenterology and nutrition · 2025Trial
- IL‑17AInternational journal of molecular medicine · 2026Article
- SULT2B1 promotes cholangiocyte epithelial-mesenchymal transition in biliary atresia: one baby step or a giant leap in the pathogenesis of biliary atresia?Pediatric research · 2026Article
- Diagnostic dilemma of cystic biliary atresia: A series of two cases and brief review of the diagnostic modalities.JPGN reports · 2026Article
- Lack of association between cytomegalovirus infection and liver fibrosis in patients with biliary atresia after the Kasai procedure.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Medium-chain triglyceride supplementation in infants with biliary atresia: a review of the evidence for impacts on fat absorption, growth, nutritional status and clinical outcomes.The Proceedings of the Nutrition Society · 2026Review
- Comparison of preoperative serum MMP-7 to liver two-dimensional shear wave elastography and its integration into a novel nomogram for predicting the native liver survival of infants with biliary atresia.Quantitative imaging in medicine and surgery · 2026Article
- The bile acid-gut microbiota-vitamin D axis: new insights into biliary atresia.Frontiers in cellular and infection microbiology · 2026Review
- Fecal microbiome profiles in infants with biliary atresia versus nonbiliary atresia cholestasis: a pilot study.Clinical and experimental pediatrics · 2025Article
- Prognostic biomarkers of biliary atresia-are we there yet?Pediatric research · 2025Article
- Review
- Research on biliary atresia and epigenetic factors from the perspective of transcriptomics: identification of key genes and experimental validation.Frontiers in pediatrics · 2025Article
- Organoids in biliary atresia.World journal of pediatric surgery · 2025Review
- Molecular Mechanisms of Fibrosis in Cholestatic Liver Diseases and Regenerative Medicine-Based Therapies.Cells · 2024Review
- Immunology of Biliary Atresia.Seminars in pediatric surgery · 2024Review
- Biliary atresia.Nature reviews. Disease primers · 2024Review
- Major surgical conditions of childhood and their lifelong implications: comprehensive review.BJS open · 2024Review
- Diseases of bile duct in children.World journal of gastroenterology · 2024Review
- Preoperative imaging findings to predict 2-year native liver survival after the Kasai procedure in patients with biliary atresia.European radiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biliary atresia (BA) is an obliterative condition of the biliary tract that presents with persistent jaundice and pale stools typically in the first few weeks of life. While this phenotypic signature may be broadly similar by the time of presentation, it is likely that this is only the final common pathway with a number of possible preceding causative factors and disparate pathogenic mechanisms-i.e., aetiological heterogeneity. Certainly, there are distinguishable variants which suggest a higher degree of aetiological homogeneity such as the syndromic variants of biliary atresia splenic malformation or cat-eye syndrome, which implicate an early developmental mechanism. In others, the presence of synchronous viral infection also make this plausible as an aetiological agent though it is likely that disease onset is from the perinatal period. In the majority of cases, currently termed isolated BA, there are still too few clues as to aetiology or indeed pathogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.