Evidence map›Paper›PMID 34884351›Full record

ArticleJournal of clinical medicine2021

Impact of COVID-19 Lockdown on Preterm Births, Low Birthweights and Stillbirths: A Retrospective Cohort Study.

Charles Garabedian, Ninon Dupuis, Christophe Vayssière, Laurence Bussières, Yves Ville, Benoît Renaudin, Louise Dugave, Norbert Winer, Nathalie Banaszkiewicz, Patrick Rozenberg and 4 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Charles GarabedianCHU Lille, Department of Obstetrics, F 59000 Lille, France.ORCID 0000-0003-2105-9784
Ninon DupuisDepartment of Obstetrics and Gynecology, Paule de Viguier Hospital, CHU Toulouse, 31059 Toulouse, France.ORCID 0000-0003-2438-9412
Christophe VayssièreDepartment of Obstetrics and Gynecology, Paule de Viguier Hospital, CHU Toulouse, 31059 Toulouse, France.
Laurence BussièresObstetrics, Fetal Surgery, Medicine and Imaging Department, AP-HP, Hôpital Necker-Enfants Malades, 75007 Paris, France.
Yves VilleObstetrics, Fetal Surgery, Medicine and Imaging Department, AP-HP, Hôpital Necker-Enfants Malades, 75007 Paris, France.
Benoît RenaudinObstetrics, Fetal Surgery, Medicine and Imaging Department, AP-HP, Hôpital Necker-Enfants Malades, 75007 Paris, France.
Louise DugaveCHU Lille, Department of Obstetrics, F 59000 Lille, France.
Norbert WinerObstetrics and Gynecology Department, Centre Hospitalier Universitaire de Nantes, University Nantes, 44035 Nantes, France.
Nathalie BanaszkiewiczObstetrics and Gynecology Department, Centre Hospitalier Universitaire de Nantes, University Nantes, 44035 Nantes, France.
Patrick RozenbergDepartment of Obstetrics and Gynecology, Poissy-Saint Germain Hospital, 78300 Poissy, France.
Manon DefranceDepartment of Obstetrics and Gynecology, Poissy-Saint Germain Hospital, 78300 Poissy, France.
Marie-Laure LegrisDepartment of Obstetrics and Gynecology, University Hospital of Strasbourg, Avenue Moliere, 67000 Strasbourg, France.
Thibaud QuibelDepartment of Obstetrics and Gynecology, Poissy-Saint Germain Hospital, 78300 Poissy, France.
Philippe DeruelleDepartment of Obstetrics and Gynecology, University Hospital of Strasbourg, Avenue Moliere, 67000 Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe effect of lockdowns during the coronavirus (COVID-19) pandemic on pregnancy outcomes remains uncertain. We aimed to evaluate the association between the COVID-19-related lockdown and pregnancy outcomes in maternity hospitals in France. STUDY

designThis was a retrospective cohort study from six tertiary referral hospitals in different regions of France. Three 55-day periods were compared: pre-lockdown from 22 January 2020, lockdown from 17 March 2020, and post-lockdown from 11 May 2020 to 4 July 2020. We included all women who delivered singleton or multiple pregnancies, who delivered at ≥24 weeks of gestation and with birthweights ≥500 g. We documented gestational ages at the delivery of liveborn and stillborn infants ('stillbirths'). These were categorized as having a very low birthweight (VLBW, <1500 g), or a low birthweight (LBW, <2500 g). Adjustments were made for place of birth, maternal age, parity and diabetes, and hypertensive disorders, as well as for multiple pregnancies.

resultsIn total, 11,929 women delivered in the six selected centers. This figure is constituted of 4093, 3829, and 4007 deliveries in the pre-lockdown (1), peri-lockdown (2), and post-lockdown (3) periods, respectively. There were no differences in pregnancy outcomes between these three periods. Overall, birth rates <27

conclusionThe pregnancy outcomes (preterm birth, LBW, VLBW, and stillbirth rates) were not modified by the COVID-19 lockdown in our cohort study in France. Considering the discrepancies in results and methodological issues in previous published studies, there is not sufficient evidence to conclude that such lockdowns have any impact on perinatal outcomes.

Indexed as

COVID-19 pandemiclow birthweightpregnancypreterm birthstillbirth

Identifiers

PMID34884351
PMCPMC8658711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.