Evidence map›Paper›PMID 34884337›Full record

ArticleJournal of clinical medicine2021

Oral Antibiotic Prophylaxis Lowers Surgical Site Infection in Elective Colorectal Surgery: Results of a Pragmatic Cohort Study in Catalonia.

Josep M Badia, Miriam Flores-Yelamos, Ana Vázquez, Nares Arroyo-García, Mireia Puig-Asensio, David Parés, Miguel Pera, Joaquín López-Contreras, Enric Limón, Miquel Pujol and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Josep M BadiaDepartment of Surgery, Hospital General Granollers, 08348 Granollers, Barcelona, Spain.ORCID 0000-0003-2928-5233
Miriam Flores-YelamosDepartment of Surgery, Hospital General Granollers, 08348 Granollers, Barcelona, Spain.
Ana VázquezServei d'Estadística Aplicada, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain.
Nares Arroyo-GarcíaDepartment of Surgery, Hospital General Granollers, 08348 Granollers, Barcelona, Spain.
Mireia Puig-AsensioDepartment of Infectious Diseases, Hospital Universitari de Bellvitge, Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0005), 08907 L'Hospitalet del Llobregat, Barcelona, Spain.
David ParésDepartment of Surgery, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Barcelona, Spain.
Miguel PeraDepartment of Surgery, Hospital del Mar, 08003 Barcelona, Catalonia, Spain.
Joaquín López-ContrerasInfectious Disease Unit, Hospital de la Santa Creu i Sant Pau-Institut d'Investigació Biomèdica Sant Pau, 08041 Barcelona, Barcelona, Spain.ORCID 0000-0002-3166-4016
Enric LimónVINCat Program, 08028 Barcelona, Catalonia, Spain.ORCID 0000-0002-5396-1521
Miquel PujolDepartment of Infectious Diseases, Hospital Universitari de Bellvitge, Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0005), 08907 L'Hospitalet del Llobregat, Barcelona, Spain.
Members Of The VINCat Colorectal Surveillance Team
Universitat Internacional de Catalunya · ESBellvitge University Hospital · ESHospital Del Mar · ESHospital de Sant Pau · ESHospital Universitari Germans Trias i Pujol · ESReig Jofre (Spain) · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of oral antibiotic prophylaxis (OAP) and mechanical bowel preparation (MBP) in the prevention of surgical site infection (SSI) after colorectal surgery is still controversial. The aim of this study was to analyze the effect of a bundle including both measures in a National Infection Surveillance Network in Catalonia.

methodsPragmatic cohort study to assess the effect of OAP and MBP in reducing SSI rate in 65 hospitals, comparing baseline phase (BP: 2007-2015) with implementation phase (IP: 2016-2019). To compare the results, a logistic regression model was established.

resultsOut of 34,421 colorectal operations, 5180 had SSIs (15.05%). Overall SSI rate decreased from 18.81% to 11.10% in BP and IP, respectively (OR 0.539, CI

conclusionsoral antibiotic prophylaxis decreased the rates of SSI and O/S-SSI in a large series of elective colorectal surgery.

Indexed as

colorectal surgerymechanical bowel preparationoral antibiotic prophylaxispreventative measuressurgical site infectionsurgical wound infection

Identifiers

PMID34884337
PMCPMC8658297
OpenAlexW3217145135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.