Evidence map›Paper›PMID 34884311›Full record

ArticleJournal of clinical medicine2021

Clinical Characteristics and Management of Angioedema Attacks in Polish Adult Patients with Hereditary Angioedema Due to C1-Inhibitor Deficiency.

Katarzyna Piotrowicz-Wójcik, Małgorzata Bulanda, Aldona Juchacz, Joanna Jamróz-Brzeska, Jacek Gocki, Krzysztof Kuziemski, Robert Pawłowicz, Grzegorz Porebski

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Katarzyna Piotrowicz-WójcikDepartment of Clinical and Environmental Allergology, Jagiellonian University Medical College, Botaniczna 3, 31-503 Krakow, Poland.
Małgorzata BulandaDepartment of Clinical and Environmental Allergology, Jagiellonian University Medical College, Botaniczna 3, 31-503 Krakow, Poland.ORCID 0000-0002-6023-260X
Aldona JuchaczGreater Poland Center of Pulmonology and Thoracic Surgery, Szamarzewskiego 62, 60-569 Poznan, Poland.
Joanna Jamróz-BrzeskaDepartment of Immunology and Allergy, Medical University of Lodz, Tadeusza Kościuszki 4, 90-419 Lodz, Poland.
Jacek GockiSpecialist Clinical Practice Allergoderm, Jagiellońska 111/3, 85-027 Bydgoszcz, Poland.ORCID 0000-0002-2029-6668
Krzysztof KuziemskiDepartment of Pulmonology and Allergology, Faculty of Medicine, Medical University of Gdansk, Smoluchowskiego 17, 80-214 Gdansk, Poland.
Robert PawłowiczDepartment and Clinic of Internal Medicine Pneumology and Allergology, Wroclaw Medical University, Marii Skłodowskiej-Curie 66, 50-369 Wrocław, Poland.
Grzegorz PorebskiDepartment of Clinical and Environmental Allergology, Jagiellonian University Medical College, Botaniczna 3, 31-503 Krakow, Poland.ORCID 0000-0002-6146-0188
Jagiellonian University · PLGdańsk Medical University · PLMedical University of Lodz · PLWroclaw Medical University · PL

Funding

Jagiellonian University N41/DBS/000500
6 · The paper itself

Abstract

Hereditary angioedema (HAE) due to C1-inhibitor (C1-INH) deficiency is a rare disease characterized by recurrent swellings. This study aims to determine (i) the clinical characteristics of the HAE patient population from Poland, and (ii) real-life patients' treatment practices. A cross-sectional study involved 138 adult HAE patients (88 females, 50 males) treated in six regional HAE centers in Poland. Consecutive patients during routine follow-up visits underwent a structured medical interview on the clinical characteristics of the course and treatment of HAE attacks within the last six months. A total of 118 of 138 patients was symptomatic. They reported in total 2835 HAE attacks predominantly peripheral and abdominal, treated with plasma-derived C1-INH (61.4%), icatibant (36.7%) and recombinant C1-INH (1.9%). An amount of 116 patients carried the rescue medication with them while traveling, and 74 patients self-administrated on demand treatment. There were twice as many symptomatic women (

Indexed as

bradykinin-mediated angioedemaC1-inhibitor deficiencyemergencyhereditary angioedematreatment

Identifiers

PMID34884311
PMCPMC8658320
OpenAlexW3217422842

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.