Evidence map›Paper›PMID 34884294›Full record

ArticleJournal of clinical medicine2021

Impact of Non-Valvular Non-Coronary Concomitant Procedures on Outcomes of Surgical Aortic Valve Replacement in Intermediate Risk Patients.

Fanar Mourad, Ali Haddad, Janine Nowak, Mohamed Elbarraki, Yacine Elhmidi, Marinela Jasarevic, Philipp Marx, Ender Demircioglu, Daniel Wendt, Matthias Thielmann and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Fanar MouradDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, 45147 Essen, Germany.
Ali HaddadDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital Essen, 45147 Essen, Germany.
Janine NowakDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, 45147 Essen, Germany.
Mohamed ElbarrakiDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, 45147 Essen, Germany.
Yacine ElhmidiDepartment of Cardiac Surgery, Ludwigshafen Heart Centre, 67063 Ludwigshafen, Germany.
Marinela JasarevicDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, 45147 Essen, Germany.
Philipp MarxDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, 45147 Essen, Germany.
Ender DemirciogluDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, 45147 Essen, Germany.
Daniel WendtDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, 45147 Essen, Germany.
Matthias ThielmannDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, 45147 Essen, Germany.ORCID 0000-0002-1007-2871
Bastian SchmackDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, 45147 Essen, Germany.
Arjang RuhparwarDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, 45147 Essen, Germany.
Sharaf-Eldin ShehadaDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, 45147 Essen, Germany.ORCID 0000-0003-1638-0493
West German Heart and Vascular Center Essen · DEEssen University Hospital · DEKlinikum Ludwigshafen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionadvanced age and concomitant procedures could increase the risk of perioperative complications during surgical aortic valve replacement (SAVR). We aimed to evaluate results of elderly patients undergoing SAVR and evaluate the impact of concomitant non-valvular, non-coronary procedures on the outcomes.

methodsA retrospective single-centre study, evaluating 464 elderly patients (mean age = 75.6 ± 4 years) undergoing either isolated-SAVR (I-SAVR = 211) or combined-SAVR (C-SAVR = 253) between 01/2007 and 12/2017. Combined-SAVR involved non-valvular, non-coronary procedures. Study endpoints are postoperative results concerning the VARC-II criteria, valve dysfunction, long-term freedom from redo-AVR and survival.

resultsmales were 52.8%. Patients had an intermediate risk profile (mean EuroSCORE-II (%) 5.2 ± 5). Postoperative results reported no significant differences in incidence of re-exploration for bleeding (6.6% vs. 6.7%, p = 1.0), stroke (0.9% vs. 0.4%, p = 0.59), dialysis (6.2% vs. 9.5%, p = 0.23) and pacemaker implantation (3.3% vs. 2.8%, p = 0.79) between I-SAVR and C-SAVR groups. Thirty-day (2.4% vs. 7.1% p = 0.03), one-year (5.7% vs. 13.8%, p = 0.003) and overall mortality (24.6% vs. 37.5%, p = 0.002) were lower in the isolated-SAVR group. Re-AVR was indicated in 1.7% of patients due to endocarditis.

conclusionsSAVR in elderly patients offers good outcomes with increased life quality and rare re-operation for structural valvular deterioration. Mortality rates were significantly higher when SAVR was combined with another "non-valvular, non-coronary" procedure.

Indexed as

intermediate risk patientsisolated and combined aortic valve replacementsurgical aortic valve replacement

Identifiers

PMID34884294
PMCPMC8658681
OpenAlexW3217373666

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.