Evidence map›Paper›PMID 34884293›Full record

ArticleJournal of clinical medicine2021

Heart Rate in Patients with SARS-CoV-2 Infection: Prevalence of High Values at Discharge and Relationship with Disease Severity.

Alessandro Maloberti, Nicola Ughi, Davide Paolo Bernasconi, Paola Rebora, Iside Cartella, Enzo Grasso, Deborah Lenoci, Francesca Del Gaudio, Michela Algeri, Sara Scarpellini and 11 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  5. Article
  6. Review
  7. Autoimmunity in Long Covid and POTS.Oxford open immunology · 2023
    Review
  8. Article
  9. Article
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 2 institutions in 1 country.

Alessandro MalobertiCardiology 4, "A.De Gasperis" Cardio Center, ASST GOM Niguarda Cà Granda, 20162 Milan, Italy.ORCID 0000-0002-2612-6264
Nicola UghiRheumatology, Multispecialist Medical Department, ASST GOM Niguarda Ca' Granda, 20162 Milan, Italy.
Davide Paolo BernasconiBicocca Bioinformatics, Biostatistics and Bioimaging Centre-B4, School of Medicine and Surgery, University of Milano Bicocca, 20126 Milan, Italy.
Paola ReboraBicocca Bioinformatics, Biostatistics and Bioimaging Centre-B4, School of Medicine and Surgery, University of Milano Bicocca, 20126 Milan, Italy.
Iside CartellaSchool of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.
Enzo GrassoSchool of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0003-4321-3455
Deborah LenociRheumatology, Multispecialist Medical Department, ASST GOM Niguarda Ca' Granda, 20162 Milan, Italy.
Francesca Del GaudioRheumatology, Multispecialist Medical Department, ASST GOM Niguarda Ca' Granda, 20162 Milan, Italy.
Michela AlgeriCardiology 4, "A.De Gasperis" Cardio Center, ASST GOM Niguarda Cà Granda, 20162 Milan, Italy.
Sara ScarpelliniCardiology 4, "A.De Gasperis" Cardio Center, ASST GOM Niguarda Cà Granda, 20162 Milan, Italy.ORCID 0000-0002-2134-6137
Enrico PernaCardiology 2, "A.De Gasperis" Cardio Center, ASST GOM Niguarda Ca' Granda, 20162 Milan, Italy.
Alessandro VerdeCardiology 2, "A.De Gasperis" Cardio Center, ASST GOM Niguarda Ca' Granda, 20162 Milan, Italy.ORCID 0000-0003-3917-2355
Caterina SantolamazzaTerritorial Cardiology "A.De Gasperis" Cardio Center, ASST GOM Niguarda Ca' Granda, 20162 Milan, Italy.
Francesco VicariTerritorial Cardiology "A.De Gasperis" Cardio Center, ASST GOM Niguarda Ca' Granda, 20162 Milan, Italy.
Maria FrigerioCardiology 2, "A.De Gasperis" Cardio Center, ASST GOM Niguarda Ca' Granda, 20162 Milan, Italy.
Antonia AlbertiTerritorial Cardiology "A.De Gasperis" Cardio Center, ASST GOM Niguarda Ca' Granda, 20162 Milan, Italy.
Maria Grazia ValsecchiBicocca Bioinformatics, Biostatistics and Bioimaging Centre-B4, School of Medicine and Surgery, University of Milano Bicocca, 20126 Milan, Italy.
Claudio RossettiNuclear Medicine, ASST GOM Niguarda Ca' Granda, 20162 Milan, Italy.
Oscar Massimiliano EpisBicocca Bioinformatics, Biostatistics and Bioimaging Centre-B4, School of Medicine and Surgery, University of Milano Bicocca, 20126 Milan, Italy.
Cristina GiannattasioCardiology 4, "A.De Gasperis" Cardio Center, ASST GOM Niguarda Cà Granda, 20162 Milan, Italy.
On The Behalf Of The Niguarda Covid-Working Group
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITUniversity of Milano-Bicocca · IT

Funding

A. De Gasperis Cardiology and Cardiac Surgery Foundation N/AItalian Ministry of University and Research (MIUR) Department of Excellence project PREMIA (PREcision MedIcine Approach: bringing biomarker research to clinic)
6 · The paper itself

Abstract

The most common arrhythmia associated with COronaVIrus-related Disease (COVID) infection is sinus tachycardia. It is not known if high Heart Rate (HR) in COVID is simply a marker of higher systemic response to sepsis or if its persistence could be related to a long-term autonomic dysfunction. The aim of our work is to assess the prevalence of elevated HR at discharge in patients hospitalized for COVID-19 and to evaluate the variables associated with it. We enrolled 697 cases of SARS-CoV2 infection admitted in our hospital after February 21 and discharged within 23 July 2020. We collected data on clinical history, vital signs, laboratory tests and pharmacological treatment. Severe disease was defined as the need for Intensive Care Unit (ICU) admission and/or mechanical ventilation. Median age was 59 years (first-third quartile 49, 74), and male was the prevalent gender (60.1%). 84.6% of the subjects showed a SARS-CoV-2 related pneumonia, and 13.2% resulted in a severe disease. Mean HR at admission was 90 ± 18 bpm with a mean decrease of 10 bpm to discharge. Only 5.5% of subjects presented HR > 100 bpm at discharge. Significant predictors of discharge HR at multiple linear model were admission HR (mean increase = β = 0.17 per bpm, 95% CI 0.11; 0.22,

Indexed as

COVID-19heart rateinfection severitySARS-CoV-2

Identifiers

PMID34884293
PMCPMC8658577
OpenAlexW3215956491

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.