Evidence map›Paper›PMID 34884186›Full record

ArticleJournal of clinical medicine2021

Hemodialysis Effect on the Composition of the Eye Fluid of Cataract Patients.

Joanna Dolar-Szczasny, Jolanta Flieger, Beata Kowalska, Dariusz Majerek, Małgorzata Tatarczak-Michalewska, Izabela Zakrocka, Wojciech Załuska, Robert Rejdak

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Joanna Dolar-SzczasnyChair and Department of General and Pediatric Ophthalmology, Medical University of Lublin, Chmielna 1, 20-079 Lublin, Poland.ORCID 0000-0003-4206-4371
Jolanta FliegerDepartment of Analytical Chemistry, Medical University of Lublin, Chodźki 4A, 20-093 Lublin, Poland.ORCID 0000-0001-6881-3161
Beata KowalskaDepartment of Water Supply and Wastewater Disposal, Lublin University of Technology, Nadbystrzycka 40B, 20-618 Lublin, Poland.
Dariusz MajerekDepartment of Applied Mathematics, University of Technology, Nadbystrzycka 38D, 20-618 Lublin, Poland.ORCID 0000-0002-0035-7187
Małgorzata Tatarczak-MichalewskaDepartment of Analytical Chemistry, Medical University of Lublin, Chodźki 4A, 20-093 Lublin, Poland.ORCID 0000-0001-5353-9091
Izabela ZakrockaChair and Department of Nephrology, Medical University of Lublin, Jaczewskiego 8, 20-090 Lublin, Poland.ORCID 0000-0001-5251-7763
Wojciech ZałuskaChair and Department of Nephrology, Medical University of Lublin, Jaczewskiego 8, 20-090 Lublin, Poland.ORCID 0000-0001-6043-3236
Robert RejdakChair and Department of General and Pediatric Ophthalmology, Medical University of Lublin, Chmielna 1, 20-079 Lublin, Poland.
Medical University of Lublin · PLLublin University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous reports have proven that dialysis patients experience disturbances in the levels of elements in biological fluids. Disturbances in the homeostasis of essential elements or the appearance of highly toxic elements are serious problems also in clinical ophthalmology. The purpose of this study was to investigate the influence of hemodialysis (HD) on the elemental composition of anterior chamber aqueous humor (AH) in patients undergoing cataract surgery. The study involved 22 patients. The control group enrolled 16 patients (age 75.68 ± 9.67, female 54.55%, male 45.45%) with cataract and normal kidney function (control), and the second group included six patients (age 70.33 ± 12.74, female 33.33%, male 66.67%) with cataract undergoing HD treatment. The elements quantification was established using an inductively coupled plasma optical emission spectrometer (ICP-MS). In the eye fluid of dialysis patients, there were increased levels of manganese (Mn) and mercury (Hg) and decreased levels of vanadium (V) and zinc (Zn). In addition, a statistically significant increase in the Hg/Zn and Hg/selenium (Se) ratios and a lowering of the iron (Fe)/Mn ratio were observed in the studied group in comparison to the control. The obtained results indicated the need for Zn and Se supplementation in order to eliminate the hazards caused by Hg toxicity. A lower level of V in the eye fluid of dialysis patients may have a positive effect on maintaining a calcium and phosphorus homeostasis. Our study gives a deep insight into changes of elements concentrations in AH induced by HD.

Indexed as

aqueous humorcataracthemodialysisICP-MStrace elements

Identifiers

PMID34884186
PMCPMC8658160
OpenAlexW3216636335

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.