Evidence map›Paper›PMID 34884172›Full record

ArticleJournal of clinical medicine2021

Longitudinal Assessment of Health and Quality of Life of COVID-19 Patients Requiring Intensive Care-An Observational Study.

Johanna Erber, Johannes R Wießner, Gregor S Zimmermann, Petra Barthel, Egon Burian, Fabian Lohöfer, Eimo Martens, Hrvoje Mijočević, Sebastian Rasch, Roland M Schmid and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Long-Term Consequences of COVID-19 at 6 Months and Above: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  2. Health-Related Quality of Life and Functional Status of Post-COVID-19 Patients.International journal of environmental research and public health · 2025
    Article
  3. Article
  4. Article
  5. One-year follow-up of depression, anxiety, and quality of life of Peruvian patients who survived COVID-19.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Johanna ErberDepartment of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0001-6614-6051
Johannes R WießnerDepartment of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Gregor S ZimmermannDepartment of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0003-0353-2523
Petra BarthelDepartment of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Egon BurianInstitute of Diagnostic and Interventional Radiology, University Hospital Rechts der ISAR, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Fabian LohöferInstitute of Diagnostic and Interventional Radiology, University Hospital Rechts der ISAR, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Eimo MartensDepartment of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0002-5801-0901
Hrvoje MijočevićInstitute of Virology, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Sebastian RaschDepartment of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Roland M SchmidDepartment of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Christoph D SpinnerDepartment of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0002-3875-5367
Rickmer BrarenInstitute of Diagnostic and Interventional Radiology, University Hospital Rechts der ISAR, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Jochen SchneiderDepartment of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0002-0300-0159
Tobias LahmerDepartment of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
TUM Klinikum · DETechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term health consequences in survivors of severe COVID-19 remain unclear. Eighteen COVID-19 patients admitted to the intensive care unit at the University Hospital Rechts der Isar, Munich, Germany, between 14 March and 23 June 2020, were prospectively followed-up at a median of 36, 75.5, 122 and 222 days after discharge. The health-related quality of life (HrQoL) (36-item Short Form Health Survey and St. George's Respiratory Questionnaire, SGRQ), cardiopulmonary function, laboratory parameters and chest imaging were assessed longitudinally. The HrQoL assessment revealed a reduced physical functioning, as well as increased SGRQ impact and symptoms scores that all improved over time but remained markedly impaired compared to the reference groups. The median radiological severity scores significantly declined; persistent abnormalities were found in 33.3% of the patients on follow-up. A reduced diffusion capacity was the most common abnormal pulmonary function parameter. The length of hospitalization correlated with role limitations due to physical problems, the SGRQ symptom and the impact score. In conclusion, in survivors of severe COVID-19, the pulmonary function and symptoms improve over time, but impairments in their physical function and diffusion capacity can persist over months. Longer follow-up studies with larger cohorts will be necessary to comprehensively characterize long-term sequelae upon severe COVID-19 and to identify patients at risk.

Indexed as

COVID-19 sequelaehealth-related quality of lifelong-term health consequencespulmonary function testSARS-CoV-2

Identifiers

PMID34884172
PMCPMC8658191
OpenAlexW3215446642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.