Evidence map›Paper›PMID 34884157›Full record

ArticleSensors (Basel, Switzerland)2021

Efficient Chemical Surface Modification Protocol on SiO

Ana L Hernandez, Sidharam P Pujari, María F Laguna, Beatriz Santamaría, Han Zuilhof, Miguel Holgado

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana L HernandezCentre for Biomedical Technology, Universidad Politécnica de Madrid, Campus de Montegancedo, Pozuelo de Alarcon, 28223 Madrid, Spain.
Sidharam P PujariLaboratory of Organic Chemistry, Wageningen University & Research, Stippeneng 4, WE 6708 Wageningen, The Netherlands.ORCID 0000-0003-0479-8884
María F LagunaCentre for Biomedical Technology, Universidad Politécnica de Madrid, Campus de Montegancedo, Pozuelo de Alarcon, 28223 Madrid, Spain.ORCID 0000-0002-1580-4509
Beatriz SantamaríaCentre for Biomedical Technology, Universidad Politécnica de Madrid, Campus de Montegancedo, Pozuelo de Alarcon, 28223 Madrid, Spain.
Han ZuilhofLaboratory of Organic Chemistry, Wageningen University & Research, Stippeneng 4, WE 6708 Wageningen, The Netherlands.ORCID 0000-0001-5773-8506
Miguel HolgadoCentre for Biomedical Technology, Universidad Politécnica de Madrid, Campus de Montegancedo, Pozuelo de Alarcon, 28223 Madrid, Spain.

Funding

European Commission 614057European Commission 844464Ministry of Economy, Industry and Competitiveness TEC2017-84846-R
6 · The paper itself

Abstract

The bioreceptor immobilization process (biofunctionalization) turns to be one of the bottlenecks when developing a competent and high sensitivity label-free biosensor. Classical approaches seem to be effective but not efficient. Although biosensing capacities are shown in many cases, the performance of the biosensor is truncated by the inefficacious biofunctionalization protocol and the lack of reproducibility. In this work, we describe a unique biofunctionalization protocol based on chemical surface modification through silane chemistry on SiO

Indexed as

Biosensing TechniquesSilicon DioxideMatrix Metalloproteinase 9Reproducibility of ResultsSurface PropertiesTransducersMatrix Metalloproteinase 9Silicon Dioxidebiofunctionalizationlabel free biosensorsurface characterizationsurface modification

Identifiers

PMID34884157
PMCPMC8662398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.