Evidence map›Paper›PMID 34884136›Full record

ArticleSensors (Basel, Switzerland)2021

Vital Signs Prediction for COVID-19 Patients in ICU.

Ahmed Youssef Ali Amer, Femke Wouters, Julie Vranken, Pauline Dreesen, Dianne de Korte-de Boer, Frank van Rosmalen, Bas C T van Bussel, Valérie Smit-Fun, Patrick Duflot, Julien Guiot and 5 more

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ahmed Youssef Ali AmerE-MEDIA, STADIUS, Department of Electrical Engineering (ESAT), Campus Group T, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-5347-9009
Femke WoutersLimburg Clinical Research Center/Mobile Health Unit, Faculty of Medicine and Life Sciences, Hasselt University, 3500 Hasselt, Belgium.ORCID 0000-0002-4420-6372
Julie VrankenLimburg Clinical Research Center/Mobile Health Unit, Faculty of Medicine and Life Sciences, Hasselt University, 3500 Hasselt, Belgium.ORCID 0000-0002-2691-0569
Pauline DreesenLimburg Clinical Research Center/Mobile Health Unit, Faculty of Medicine and Life Sciences, Hasselt University, 3500 Hasselt, Belgium.ORCID 0000-0003-4165-6121
Dianne de Korte-de BoerDepartment of Anesthesiology and Pain Management, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0003-4688-8300
Frank van RosmalenDepartment of Intensive Care, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0002-9522-3711
Bas C T van BusselDepartment of Intensive Care, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0003-1621-7848
Valérie Smit-FunDepartment of Anesthesiology and Pain Management, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0001-5528-853X
Patrick DuflotService des Applications Informatiques, Centre Hospitalier Universitaire de Liège-CHU, 4000 Liège, Belgium.ORCID 0000-0001-5378-5217
Julien GuiotRespiratory Medicine, Centre Hospitalier Universitaire de Liège-CHU, 4000 Liège, Belgium.ORCID 0000-0001-7800-1730
Iwan C C van der HorstDepartment of Intensive Care, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0003-3891-8522
Dieter MesottenLimburg Clinical Research Center/Mobile Health Unit, Faculty of Medicine and Life Sciences, Hasselt University, 3500 Hasselt, Belgium.
Pieter VandervoortLimburg Clinical Research Center/Mobile Health Unit, Faculty of Medicine and Life Sciences, Hasselt University, 3500 Hasselt, Belgium.
Jean-Marie AertsMeasure, Model & Manage Bioresponses (M3-BIORES), Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-5548-9163
Bart VanrumsteE-MEDIA, STADIUS, Department of Electrical Engineering (ESAT), Campus Group T, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-9409-935X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study introduces machine learning predictive models to predict the future values of the monitored vital signs of COVID-19 ICU patients. The main vital sign predictors include heart rate, respiration rate, and oxygen saturation. We investigated the performances of the developed predictive models by considering different approaches. The first predictive model was developed by considering the following vital signs: heart rate, blood pressure (systolic, diastolic and mean arterial, pulse pressure), respiration rate, and oxygen saturation. Similar to the first approach, the second model was developed using the same vital signs, but it was trained and tested based on a leave-one-subject-out approach. The third predictive model was developed by considering three vital signs: heart rate (HR), respiration rate (RR), and oxygen saturation (SpO2). The fourth model was a leave-one-subject-out model for the three vital signs. Finally, the fifth predictive model was developed based on the same three vital signs, but with a five-minute observation rate, in contrast with the aforementioned four models, where the observation rate was hourly to bi-hourly. For the five models, the predicted measurements were those of the three upcoming observations (on average, three hours ahead). Based on the obtained results, we observed that by limiting the number of vital sign predictors (i.e., three vital signs), the prediction performance was still acceptable, with the average mean absolute percentage error (MAPE) being 12%,5%, and 21.4% for heart rate, oxygen saturation, and respiration rate, respectively. Moreover, increasing the observation rate could enhance the prediction performance to be, on average, 8%,4.8%, and 17.8% for heart rate, oxygen saturation, and respiration rate, respectively. It is envisioned that such models could be integrated with monitoring systems that could, using a limited number of vital signs, predict the health conditions of COVID-19 ICU patients in real-time.

Indexed as

COVID-19Oxygen SaturationHumansIntensive Care UnitsSARS-CoV-2Vital SignsCOVID-19ICUkNN-LS-SVMvital signs prediction

Identifiers

PMID34884136
PMCPMC8662454

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.