Evidence map›Paper›PMID 34883720›Full record

ArticlePolymers2021

Fabrication of Tizanidine Loaded Patches Using Flaxseed Oil and Coriander Oil as a Penetration Enhancer for Transdermal Delivery.

Muhammad Akhlaq, Abul Kalam Azad, Shivkanya Fuloria, Dhanalekshmi Unnikrishnan Meenakshi, Sajid Raza, Muhammad Safdar, Asif Nawaz, Vetriselvan Subramaniyan, Mahendran Sekar, Kathiresan V Sathasivam and 3 more

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  7. The Therapeutic Application ofMedicina (Kaunas, Lithuania) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Muhammad AkhlaqDepartment of Pharmaceutics, Faculty of Pharmacy, Gomal University, Dera Ismail khan 29050, Pakistan.
Abul Kalam AzadFaculty of Pharmacy, AIMST University, Bedong 08100, Malaysia.ORCID 0000-0003-4874-1169
Shivkanya FuloriaFaculty of Pharmacy, AIMST University, Bedong 08100, Malaysia.
Dhanalekshmi Unnikrishnan MeenakshiCollege of Pharmacy, National University of Science and Technology, Muscat 130, Oman.ORCID 0000-0002-2689-4079
Sajid RazaDepartment of Pharmaceutics, Faculty of Pharmacy, Gomal University, Dera Ismail khan 29050, Pakistan.
Muhammad SafdarDepartment of Pharmaceutics, Faculty of Pharmacy, Gomal University, Dera Ismail khan 29050, Pakistan.
Asif NawazDepartment of Pharmaceutics, Faculty of Pharmacy, Gomal University, Dera Ismail khan 29050, Pakistan.ORCID 0000-0002-3232-0258
Vetriselvan SubramaniyanFaculty of Medicine, Bioscience and Nursing, MAHSA University, Jalan SP 2, Bandar Saujana Putra, Jenjarom Selangor, Shah Alam 42610, Malaysia.ORCID 0000-0002-9629-9494
Mahendran SekarDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh 30450, Malaysia.ORCID 0000-0002-3022-6137
Kathiresan V SathasivamCentre of Excellence for Biomaterials Engineering, AIMST University, Bedong 08100, Malaysia.
Yuan Seng WuCentre for Virus and Vaccine Research & Department of Biological Sciences, School of Medical and Life Sciences, Sunway University, Petaling Jaya 47500, Malaysia.ORCID 0000-0001-5574-8049
Mireia Mallandrich MiretDepartment of Pharmacy, Pharmaceutical Technology and Physical-Chemistry, Faculty of Pharmacy and Sciences Food, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-9316-8459
Neeraj Kumar FuloriaFaculty of Pharmacy, AIMST University, Bedong 08100, Malaysia.
AIMST University · MYGomal University · PKMahsa University · MYSunway University · MYUniversitat de Barcelona · ESUniversity of Kuala Lumpur · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transdermal drug delivery is important to maintain plasma drug concentrations for therapeutic efficacy. The current study reports the design, formulation, and evaluation of tizanidine transdermal patches formulated using chitosan and thiolated chitosan, ethyl cellulose (EC), polyvinylpyrrolidone (PVP), and Eudragit RL100 in different ratios. The tizanidine patches were formulated using flaxseed oil and coriander oil in the concentrations of 1%

Indexed as

coriander oilethyl celluloseflaxseed oilpatchespolyvinyl pyrrolidonetizanidine

Identifiers

PMID34883720
PMCPMC8659784
OpenAlexW3215923868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.