Evidence map›Paper›PMID 34883637›Full record

ArticlePolymers2021

Collagen Scaffolds Treated by Hydrogen Peroxide for Cell Cultivation.

Yuliya Nashchekina, Pavel Nikonov, Nataliya Mikhailova, Alexey Nashchekin

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Enzymatic and non-enzymatic oxidation of fibrillar collagen.Redox report : communications in free radical research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yuliya NashchekinaCenter of Cell Technologies, Institute of Cytology of the Russian Academy of Sciences, Tikhoretsky Pr. 4, 194064 St. Petersburg, Russia.ORCID 0000-0002-4371-7445
Pavel NikonovCenter of Cell Technologies, Institute of Cytology of the Russian Academy of Sciences, Tikhoretsky Pr. 4, 194064 St. Petersburg, Russia.
Nataliya MikhailovaCenter of Cell Technologies, Institute of Cytology of the Russian Academy of Sciences, Tikhoretsky Pr. 4, 194064 St. Petersburg, Russia.ORCID 0000-0003-1650-9330
Alexey NashchekinLaboratory "Materials and Structures of Solid State Electronics", Ioffe Institute, Polytekhnicheskaya Str., 26, 194021 St. Petersburg, Russia.ORCID 0000-0002-2542-7364
Institute of Cytology · RUIoffe Institute · RU

Funding

Russian Science Foundation 21-74-20120
6 · The paper itself

Abstract

Collagen in the body is exposed to a range of influences, including free radicals, which can lead to a significant change in its structure. Modeling such an effect on collagen fibrils will allow one to get a native structure in vitro, which is important for modern tissue engineering. The aim of this work is to study the effect of free radicals on a solution of hydrogen peroxide with a concentration of 0.006-0.15% on the structure of collagen fibrils in vitro, and the response of cells to such treatment. SEM measurements show a decrease in the diameter of the collagen fibrils with an increase in the concentration of hydrogen peroxide. Such treatment also leads to an increase in the wetting angle of the collagen surface. Fourier transform infrared spectroscopy demonstrates a decrease in the signal with wave number 1084 cm

Indexed as

adipogenic stromal cellsand A-431 epidermoid carcinomacollagen fibrilshydrogen peroxideMG-63 osteosarcoma cell linescanning electron microscopy

Identifiers

PMID34883637
PMCPMC8659075
OpenAlexW3216287360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.