ArticleSleep2022
Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.
Article in Sleep, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07515417 (Effect of Magnesium Supplementation on Sleep Quality and Cognition in Saudi Adults), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Magnesium Supplementation on Sleep Quality and Cognition in Saudi Adults: A Randomized Controlled Trial
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Sleep disturbances in anorexia nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2025Pooled it
- Modulating stress and sleep through a multi-compound dietary supplement: a randomized, double-blind, placebo-controlled trial.Journal of the International Society of Sports Nutrition · 2026Trial
- Effect of finger millet diet on mental health and meta cognitive skills in young adult athletes and non-athletes.Scientific reports · 2025Trial
- Magnesium Bisglycinate Supplementation in Healthy Adults Reporting Poor Sleep: A Randomized, Placebo-Controlled Trial.Nature and science of sleep · 2025Trial
- Effects of PeptiSleep™ on sleep modification and biometrics in adults with sleep impairment: A randomised, placebo-controlled pilot study.Sleep medicine: X · 2026Article
- Association Between Serum Trace Elements and Obstructive Sleep Apnea in Iranian Adults: Multiple-exposure Models.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2026Article
- Neurobehavioural genes exert indirect genetic effects on blood lipid profiles through behavioural traits.Communications biology · 2026Article
- Dietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.Nutrition reviews · 2026Review
- Magnesium and Zinc Are Associated with Sleep Quality in Saudi Adults: Evidence from a Cross-Sectional Study.Nutrients · 2025Article
- Article
- Causal relations of trace elements and nutrients with insomnia: A Mendelian randomization study.Medicine · 2025Article
- The association between magnesium intake and circadian syndrome among US adults attending NHANES 2005-2016.Nutrition journal · 2025Article
- Integrative sleep management: from molecular pathways to conventional and herbal treatments.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Magnesium and Zinc in Schizophrenia.Biomedicines · 2025Review
- Associations between essential trace elements and sleep quality in Iranian adults based on the Pittsburgh Sleep Quality Index.Scientific reports · 2025Article
- Association between dietary micronutrient adequacy index and sleep quality, sleep duration and chronic fatigue in patients with type 2 diabetes.Journal of diabetes and metabolic disorders · 2025Article
- Banana Supplementation for Breast Cancer Surgery Patients: A Two-Center Experience.Breast care (Basel, Switzerland) · 2025Article
- Dietary Magnesium Intake Is Associated With Self-Reported Short Sleep Duration but Not Self-Reported Sleep Disorder.Brain and behavior · 2025Article
- Exploring the impact of PFAS exposure and sleep duration on kidney stone formation in the U.S. population.Frontiers in public health · 2025Article
- Dietary interventions and nutritional strategies for menopausal health: a mini review.Frontiers in nutrition · 2025Review
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 1 country.
Funding
Abstract
STUDY
objectivesAs an antagonist of calcium (Ca), magnesium (Mg) has been implicated in the regulation of sleep. We aimed to examine the longitudinal associations of Mg intake and Ca-to-Mg intake ratio (Ca:Mg) with sleep quality and duration.
methodsThe study sample consisted of 3,964 participants from the Coronary Artery Risk Development in Young Adults (CARDIA) study. Dietary and supplementary intake of Mg were obtained using the CARDIA Dietary History at baseline (1985-1986), exam years 7 and 20. Self-reported sleep outcomes were measured at years 15 and 20. Sleep quality was rating from 1 (very good) to 5 (very bad). We categorized sleep duration to <7, 7-9, and >9 h. Generalized estimating equation was used to examine the associations of interest as repeated measures at the two time points.
resultsAfter adjustment for potential confounders, Mg intake was borderline associated with better sleep quality [highest quartile (Q4) vs. intake quartile (Q1): odds ratio (OR) = 1.23; 95% CI = 0.999, 1.50, ptrend = 0.051]. Participants in Q4 were also less likely to have short sleep (<7 h) compared to those in Q1 (OR = 0.64; 95% CI = 0.51, 0.81, ptrend = 0.012). The observed association with short sleep persisted among participants without depressive disorders (Q4 vs. Q1: OR = 0.64; 95% CI = 0.49, 0.82, ptrend < 0.001), but not among individuals with depressive disorder. Ca:Mg was not associated with either outcomes, regardless of depression status.
conclusionsMg intake was associated with both sleep outcomes in this longitudinal analysis. Randomized controlled trials with objective measures of sleep are warranted to establish the potential causal inference.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.