Evidence map›Paper›PMID 34883237›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022

Ebola virus disease nosocomial infections in the Democratic Republic of the Congo: a descriptive study of cases during the 2018-2020 outbreak.

April Baller, Maria Clara Padoveze, Patrick Mirindi, Carmen Emily Hazim, Jonathan Lotemo, Jerome Pfaffmann, Aminata Ndiaye, Simone Carter, Marie-Amelie Degail Chabrat, Samuel Mangala and 20 more

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 5 institutions in 4 countries.

April BallerWorld Health Organization. Electronic address: ballera@who.int.
Maria Clara PadovezeWorld Health Organization.
Patrick MirindiWorld Health Organization.
Carmen Emily HazimCenters for Disease Control and Prevention, Atlanta, GA, USA.
Jonathan LotemoMinistry of Health, Democratic Republic of the Congo.
Jerome PfaffmannUnited Nations Children's Fund, New York, NY, USA.
Aminata NdiayeWorld Health Organization.
Simone CarterUnited Nations Children's Fund, New York, NY, USA.
Marie-Amelie Degail ChabratWorld Health Organization.
Samuel MangalaMinistry of Health, Democratic Republic of the Congo.
Berthe BanzuaMinistry of Health, Democratic Republic of the Congo.
Chantal UmutoniUnited Nations Children's Fund, New York, NY, USA.
N'Deye Rosalie NiangPAE/Macfadden.
Landry KabegoWorld Health Organization.
Abdoulaye OuedraogoWorld Health Organization.
Bienvenue HoudjoWorld Health Organization.
Didier MweshaWorld Health Organization.
Kevin Babila OusmanWorld Health Organization.
Amy KolwaiteCenters for Disease Control and Prevention, Atlanta, GA, USA.
David D BlaneyCenters for Disease Control and Prevention, Atlanta, GA, USA.
Mary J ChoiCenters for Disease Control and Prevention, Atlanta, GA, USA.
Raymond PallawoWorld Health Organization.
Anais LegandWorld Health Organization.
Benjamin ParkCenters for Disease Control and Prevention, Atlanta, GA, USA.
Pierre FormentyWorld Health Organization.
Joel M MontgomeryCenters for Disease Control and Prevention, Atlanta, GA, USA.
Abdou Salam GueyeWorld Health Organization.
Benedetta AllegranziWorld Health Organization.
N'da Kona Michel YaoWorld Health Organization.
Ibrahima Soce FallWorld Health Organization.
World Health Organization - Pakistan · PKCenters for Disease Control and Prevention · USMinistry of Public Health · CDUnited Nations Children's Fund · USSkadden Arps Slate Meagher & Flom · US

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectivesTo describe the characteristics of nosocomial cases of Ebola virus disease (EVD) in the Democratic Republic of the Congo between July 2018 and May 2020 in order to inform future interventions.

methodsNosocomial cases of EVD were identified during outbreak response surveillance, and a retrospective analysis of cases was conducted according to demographic characteristics and type of health facility (HF).

resultsOf 3481 cases of EVD, 579 (16.6%) were nosocomial. Of these, 332 cases occurred in women (57.3%). Patients and visitors accounted for 419 cases (72.4%), of which 79 (18.9%) were aged 6-≤18 years and 108 (25.8%) were aged ≤5 years. Health workers (HWs) accounted for the remaining 160 (27.6%) nosocomial cases. The case fatality rate (CFR) for HWs (66/160, 41.3%) was significantly lower than the CFR for patients and visitors (292/419, 69.7%) (P<0.001). The CFR was higher among cases aged 6-≤18 years (54/79, 68.4%) and ≤5 years (89/108, 82.4%). Referral HFs (>39 beds) had the highest prevalence of nosocomial EVD (148/579, 25.6%). Among HFs with at least one case of nosocomial infection, 50.0% (98/196) were privately owned.

conclusionsNurses and traditional healers should be targeted for infection prevention and control training, and supportive supervision should be provided to HFs to mitigate EVD transmission.

Indexed as

Cross InfectionEbolavirusHemorrhagic Fever, EbolaDemocratic Republic of the CongoDisease OutbreaksFemaleHumansRetrospective StudiesCross-infectionEbolaHealthcare-associated infectionHealth worker infectionInfection prevention and controlNosocomial infectionTransmissionViral haemorrhagic fever

Identifiers

PMID34883237
PMCPMC8755545
OpenAlexW4200222754

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.