Evidence map›Paper›PMID 34882867›Full record

ArticleProtein science : a publication of the Protein Society2022

Structural and functional characterization of fosfomycin resistance conferred by FosB from Enterococcus faecium.

Vanessa Wiltsie, Skye Travis, Madeline R Shay, Zachary Simmons, Patrick Frantom, Matthew K Thompson

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Protein science : a publication of the Protein Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Draft genome sequence ofMicrobiology resource announcements · 2026
    Article
  2. Review
  3. Structural Studies ofInternational journal of molecular sciences · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vanessa WiltsieDepartment of Chemistry & Biochemistry, The University of Alabama, Tuscaloosa, Alabama, USA.
Skye TravisDepartment of Chemistry & Biochemistry, The University of Alabama, Tuscaloosa, Alabama, USA.
Madeline R ShayDepartment of Chemistry & Biochemistry, The University of Alabama, Tuscaloosa, Alabama, USA.
Zachary SimmonsDepartment of Chemistry & Biochemistry, The University of Alabama, Tuscaloosa, Alabama, USA.
Patrick FrantomDepartment of Chemistry & Biochemistry, The University of Alabama, Tuscaloosa, Alabama, USA.
Matthew K ThompsonDepartment of Chemistry & Biochemistry, The University of Alabama, Tuscaloosa, Alabama, USA.ORCID 0000-0002-1964-3896
University of Alabama · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Gram-positive pathogen Enterococcus faecium is one of the leading causes of hospital-acquired vancomycin resistant enterococci (VRE) infections. E. faecium has extensive multidrug resistance and accounts for more than two million infections in the United States each year. FosB is a fosfomycin resistance enzyme found in Gram-positive pathogens like E. faecium. Typically, the FosB enzymes are Mn

Indexed as

Enterococcus faeciumFosfomycinVancomycin-Resistant EnterococciAnti-Bacterial AgentsKineticsAnti-Bacterial AgentsFosfomycinantimicrobial resistanceBacillithiolcrystallographyEnterococcus faeciumESKAPE pathogensFosfomycinThiol transferase

Identifiers

PMID34882867
PMCPMC8862413
OpenAlexW4200095578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.