Evidence map›Paper›PMID 34882792›Full record

ArticleThe Laryngoscope2022

Timing of Acoustic Hearing Changes After Cochlear Implantation.

Megan J Jensen, Heba Isaac, Helin Hernandez, Jacob Oleson, Camille Dunn, Bruce J Gantz, Marlan R Hansen

Open access · greenAbstract read
In one paragraph

Article in The Laryngoscope, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Megan J JensenDepartment of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa, U.S.A.
Heba IsaacDepartment of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa, U.S.A.
Helin HernandezDepartment of Biostatistics, University of Iowa, Iowa City, Iowa, U.S.A.
Jacob OlesonDepartment of Biostatistics, University of Iowa, Iowa City, Iowa, U.S.A.
Camille DunnDepartment of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa, U.S.A.ORCID 0000-0001-7839-2073
Bruce J GantzDepartment of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa, U.S.A.
Marlan R HansenDepartment of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa, U.S.A.ORCID 0000-0002-6884-4897
University of Iowa · US

Funding

Speech Production &LanguageP50DC000242 · NIDCD · UNIVERSITY OF IOWA · PI Bob McMurray · 1989 to 2026
$58.8M
The University of Iowa Clinical and Translational Science AwardUL1TR002537 · NCATS · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, WINOKUR, PATRICIA · 2018 to 2022
$20.0M
The University of Iowa Clinical and Translational Science AwardU54TR001356 · NCATS · UNIVERSITY OF IOWA · PI WINOKUR, PATRICIA · 2015 to 2016
$7.1M
Reduction of Intracochlear Trauma and Fibrosis Using Dual Network, Zwitterionic Hydrogel Thin Films on Cochlear Implant SurfacesR01DC012578 · NIDCD · UNIVERSITY OF IOWA · PI Allan Guymon, Marlan R Hansen · 2013 to 2026
$6.3M
Research Training Program in OtolaryngologyT32DC000040 · NIDCD · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R · 1993 to 2025
$5.4M
Role of Macrophages on Tissue Remodeling Following Cochlear ImplantationR01DC018488 · NIDCD · UNIVERSITY OF IOWA · PI Marlan R Hansen · 2020 to 2026
$2.8M
NCATS NIH HHS U54 TR001356NCATS NIH HHS UL1 TR002537NIDCD NIH HHS P50 DC000242NIDCD NIH HHS R01 DC012578NIDCD NIH HHS T32 DC000040
6 · The paper itself

Abstract

objectives/hypothesisTo determine the timing of acoustic hearing changes among hearing preservation Cochlear implant (CI) recipients. To determine differences in hearing outcomes based on device type and demographic factors. To determine if there is a relationship between the extent of early hearing loss after CI and the subsequent rate of continued hearing loss. STUDY

designProspective, single subject study.

methodsTwo hundred and eleven subjects who received a hearing preservation CI were included in the study-80 Nucleus Hybrid L24 (Cochlear), 47 422/522 (Cochlear), 24 S8 (Cochlear), 14 S12 (Cochlear), 6 SRW (Cochlear), 21 SLIM J (Advanced Bionics), and 19 Flex (Med-EL). Of these, 127 were included in the subsequent analyses. Audiometric thresholds (low frequency pure-tone-averages) were collected and compared pre and postoperatively.

resultsLong-term hearing preservation rates were 65% (52/80) for L24, 83% (20/24) for S8, 79% (11/14) for S12, 83% (5/6) for SRW, 54% (25/47) for 422/522, 91% (21/23) for SLIM J, and 84% (16/19) for Flex. Hearing loss was not related to device type (P = .9105) or gender (P = .2169). Older subjects (age ≥65) had worse hearing outcomes than younger subjects after initial device activation (age <65, P = .0262). There was no significant difference in rate of hearing loss over time between older and younger patients (P = .0938). Initial postoperative hearing loss was not associated with the rate of long-term hearing loss.

conclusionsLong-term low frequency hearing preservation is possible for CI recipients and is not associated with gender or device type. Rate of hearing loss over time is not dependent on patient age. Early hearing loss after CI does not predict the rate of long-term hearing loss. LEVEL OF EVIDENCE: 3 Laryngoscope, 132:2036-2043, 2022.

Indexed as

Cochlear ImplantationCochlear ImplantsDeafnessHearing LossSpeech PerceptionAcousticsAudiometry, Pure-ToneAuditory ThresholdHearingHumansProspective StudiesTreatment OutcomeCochlear implantHearing preservationTemporal dynamics

Identifiers

PMID34882792
PMCPMC9177890
OpenAlexW4200069281

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.