SynthesisPloS one2021
Human fascioliasis in Africa: A systematic review.
Synthesis in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Fasciola spp. in Southeast Asia: A systematic review.PLoS neglected tropical diseases · 2024Pooled it
- Effects of temperature on the life history traits of intermediate host snails of fascioliasis: A systematic review.PLoS neglected tropical diseases · 2023Pooled it
- Novel environmental risk index reveals uneven impact of climate change on fascioliasis risk across Africa and Europe.PLoS neglected tropical diseases · 2026Article
- Fasciolosis in a traveler returning from Burkina Faso.Food and waterborne parasitology · 2026Article
- Development of a qPCR assay for Fasciola spp. identification and a deep amplicon sequencing method for differentiation of fluke species in UK livestock.PLoS neglected tropical diseases · 2026Article
- Human infestations with Fasciola hepatica in Austria between 1955 and 2025: data from a low-incidence country.Parasite (Paris, France) · 2026Article
- Hepatic Fascioliasis Masquerading as Acute Appendicitis in a Child: A Case Report.Clinical medicine insights. Case reports · 2026Article
- High burden and multi-parasite profile of gastrointestinal infections in cattle from Limpopo District, Southern Mozambique: Epidemiology, risk factors, and One Health implications.Veterinary world · 2025Article
- In Vitro Effects of Vanadate Erbium/Silver Oxide (ErVOVeterinary medicine and science · 2025Article
- Abdominal CT scan findings of a child with hepatic fascioliasis: A case report on rarely reported emerging disease.Radiology case reports · 2025Article
- The Clinical Picture Caused byOpen forum infectious diseases · 2025Article
- Inverted Patterns of Schistosomiasis and Fascioliasis and Risk Factors Among Humans and Livestock in Northern Tanzania.Pathogens (Basel, Switzerland) · 2025Article
- Human Schistosoma exposure risk in rice fields and an exploration of fish species for snail and schistosomiasis biocontrol.PLOS global public health · 2025Article
- An overview of fasciolosis in human and cattle populations in New Valley, Egypt.Frontiers in veterinary science · 2025Article
- The impact of parasitic diseases on dromedary camel (Frontiers in veterinary science · 2025Review
- Evaluating the In Vitro Anthelmintic Activity of Zinc Oxide Nanoparticles (ZnO-NPs) Against the Adult Stages of Fasciola hepatica.Veterinary medicine and science · 2025Article
- Article
- Trematode infection in ruminants and diversity of snail hosts across three agro-ecological zones in Ethiopia.BMC veterinary research · 2024Article
- Article
- First Molecular Identification ofPathogens (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fascioliasis is a globally distributed, parasitic zoonosis, caused by Fasciola hepatica and F. gigantica. A comprehensive overview of the epidemiology of human fascioliasis in Africa is missing up to now. Therefore, our objective was to conduct a systematic review aiming to summarize recent knowledge on the distribution, prevalence, and risk factors of human fascioliasis in Africa. A key word search was performed in PubMed, Web of Science and Africa Wide, to gather relevant literature, published between the 1st of January 2000 and 31st of December 2020. A total of 472 records were initially retrieved, with 40 full text articles retained for the qualitative synthesis. Human fascioliasis was reported in 12 African countries, namely Algeria, Angola, Cape Verde, Egypt, Ethiopia, Ghana, Morocco, Nigeria, Senegal, South-Africa, Tanzania and Tunisia. The majority of the studies was conducted in Egypt. A total of 28 records were population surveys. Coproscopy was the most commonly used tool for fascioliasis diagnosis in these surveys. Gender (being female), consumption of raw vegetables/seeds, age, owning livestock, and use of unsafe drinking water sources, were identified as risk factors in 7 studies. Furthermore, 43 case reports were retrieved, described in 12 studies. Eosinophilia was present in 39 of these cases, while 11 had positive coproscopy results. Eight cases described having eaten raw wild vegetables. Overall, the low number and quality of records retrieved indicates that human fascioliasis remains a truly neglected disease in Africa, and more epidemiological studies are urgently needed to both establish the actual distribution as well as risk factors on the continent.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.