Evidence map›Paper›PMID 34882068›Full record

ArticleCancer biology & therapy2021

Targeted FGFR/VEGFR/PDGFR inhibition with dovitinib enhances the effects of nab-paclitaxel in preclinical gastric cancer models.

Kate Crawford, Erin Bontrager, Margaret A Schwarz, Apurva Chaturvedi, Daniel D Lee, Hassan Md Sazzad, Urs von Holzen, Changhua Zhang, Roderich E Schwarz, Niranjan Awasthi

Open access · bronzeAbstract read
In one paragraph

Article in Cancer biology & therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Kate CrawfordDepartment of Surgery, Indiana University School of Medicine, South Bend, IN, USA.
Erin BontragerDepartment of Surgery, Indiana University School of Medicine, South Bend, IN, USA.
Margaret A SchwarzDepartment of Pediatrics, Indiana University School of Medicine, South Bend, IN, USA.
Apurva ChaturvediDepartment of Surgery, Indiana University School of Medicine, South Bend, IN, USA.
Daniel D LeeDepartment of Pediatrics, Indiana University School of Medicine, South Bend, IN, USA.
Hassan Md SazzadDepartment of Surgery, Indiana University School of Medicine, South Bend, IN, USA.
Urs von HolzenUniversity at Buffalo, Buffalo, Ny, USA.
Changhua ZhangDepartment of Gastrointestinal Surgery, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Roderich E SchwarzUniversity at Buffalo, Buffalo, Ny, USA.
Niranjan AwasthiDepartment of Surgery, Indiana University School of Medicine, South Bend, IN, USA.ORCID 0000-0002-6477-1029
Indiana University South Bend · USUniversity of Notre Dame · USRoswell Park Comprehensive Cancer Center · USSun Yat-sen University · CNUniversity at Buffalo, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Standard chemotherapy regimens for gastric adenocarcinoma (GAC) have limited efficacy and considerable toxicity profiles.

Indexed as

Stomach NeoplasmsAlbuminsAnimalsAntineoplastic Combined Chemotherapy ProtocolsBenzimidazolesPaclitaxelQuinolonesXenograft Model Antitumor Assays130-nm albumin-bound paclitaxel4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-oneAlbuminsBenzimidazolesPaclitaxelQuinolonesCombination therapydovitinibgastric cancernab-paclitaxel

Identifiers

PMID34882068
PMCPMC8726643
OpenAlexW4200169846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.