ArticleJournal of cachexia, sarcopenia and muscle2022
Sonographic assessment of low muscle quantity identifies mortality risk during COVID-19: a prospective single-centre study.
Article in Journal of cachexia, sarcopenia and muscle, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06829290 (Influence of Sarcopenia on the Course of the Diseases - Measured Using Ultrasound and Biochemical Markers), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of Sarcopenia on the Course of the Diseases - Measured Using Ultrasound and Biochemical Markers
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Prevalence and clinical implications of abnormal body composition phenotypes in patients with COVID-19: a systematic review.The American journal of clinical nutrition · 2023Pooled it
- Osteosarcopenia as a predictor of postoperative adverse outcomes in older adults undergoing total hip arthroplasty.Journal of bone and mineral metabolism · 2026Article
- Malnutrition contribution to the functional status and health related quality of life after COVID-19, a correlational follow-up study.Scientific reports · 2024Article
- The Effects of a Pulmonary Rehabilitation Program in Severe and Critical COVID-19 Disease: A Prospective Observational Study.Journal of clinical practice and research · 2023Article
- Lower limb muscle matters in patients with hypoxic brain injury following out-of-hospital cardiac arrest.Acute and critical care · 2023Article
- Article
- Assessment of body composition in adults hospitalized with acute COVID-19: a scoping review.Frontiers in nutrition · 2023Article
- Sarcopenia and COVID-19 Outcomes.Clinical interventions in aging · 2023Review
- Nutrition support for critically ill patients during the COVID-19 pandemic: the Italian SIAARTI survey.Journal of anesthesia, analgesia and critical care · 2022Article
- Sonographic assessment of low muscle quantity identifies mortality risk during COVID-19: a prospective single-centre study.Journal of cachexia, sarcopenia and muscle · 2022Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAssessment of muscle quantity by sonographic muscle indices could help identify patients at risk for fatal outcome during coronavirus disease-2019 (COVID-19). The aim of this study was to explore sonographic muscle indices as predictors of COVID-19 outcome and to test the feasibility of sonographic muscle measurement in an isolation context.
methodsMuscle indices, derived from the psoas muscle or thigh muscles, were quantified by sonography in a cohort of patients without COVID-19 to obtain reference values for low muscle quantity. Gender-specific median of different muscle indices were defined as threshold value for low muscle quantity. The prognostic relevance of low muscle quantity, was prospectively explored in two cohorts of hospitalized COVID-19 patients. Optimal muscle index cutoff values predictive for 30 day mortality during COVID-19 were determined by receiver operating characteristic-area under the curve and Youden index calculation. Muscle quantity and known prognostic factors of COVID-19 were analysed by multivariable log-regression.
resultsCompared with other muscle indices, the psoas muscle area index (PMAI) showed the most favourable characteristics to predict outcome of COVID-19 disease. Sonographic morphometry of patients without COVID-19 (n = 136) revealed a gender-specific median for PMAI (male: 291.1 mm
conclusionsSonographic morphometry provides reliable muscle quantification under hygienic precautions and allows risk stratification of patients with COVID-19.
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