Evidence map›Paper›PMID 34881408›Full record

ArticleCell stress & chaperones2022

Protective effect of hydrogen sulfide against stress-induced lung injury: involvement of Nrf2, NFκB/iNOS, and HIF-1α signaling pathways.

Fatma F Ali, Hanaa Hassanein Mohammed, Doaa M Elroby Ali

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell stress & chaperones, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Semi-Synthetic HACS medicinal chemistry letters · 2026
    Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Fatma F AliMedical Physiology Department, Faculty of Medicine, Minia University, Minia, Egypt. fatmafarrag2008@gmail.com.ORCID 0000-0002-8289-7944
Hanaa Hassanein MohammedHistology and Cell Biology Department, Faculty of Medicine, Minia University, Minia, Egypt.
Doaa M Elroby AliBiochemistry Department, Faculty of Pharmacy, Sohag University, Sohag, Egypt.
Minia University · EGSohag University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress is a common phenomenon that is attracting increasing attention. Hydrogen sulfide (H

Indexed as

Hydrogen SulfideLung InjuryAnimalsAntioxidantsInterleukin-10MaleNF-E2-Related Factor 2NF-kappa BNitric OxideNitric Oxide Synthase Type IIRatsSignal TransductionTumor Necrosis Factor-alphaAntioxidantsHydrogen SulfideInterleukin-10NF-E2-Related Factor 2NF-kappa BNitric OxideNitric Oxide Synthase Type IITumor Necrosis Factor-alphaHypoxia-inducible factor 1 alphaLungNuclear factor erythroid 2–related factor 2Nuclear factor kappa BSodium hydrosulfideStress

Identifiers

PMID34881408
PMCPMC8821758
OpenAlexW4200401609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.