Evidence map›Paper›PMID 34881401›Full record

ArticleClinical oral investigations2022

The impact of tooth loss on cognitive function.

Pablo Galindo-Moreno, Lucia Lopez-Chaichio, Miguel Padial-Molina, Gustavo Avila-Ortiz, Francisco O'Valle, Andrea Ravida, Andres Catena

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.

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  20. Comparison of the Performance Parameters of BioHPPMaterials (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Pablo Galindo-MorenoDepartment of Oral Surgery and Implant Dentistry, School of Dentistry, University of Granada, Campus Universitario de Cartuja, s/n, 18071, Granada, Spain. pgalindo@ugr.es.ORCID http://orcid.org/0000-0002-6614-6470
Lucia Lopez-ChaichioDepartment of Oral Surgery and Implant Dentistry, School of Dentistry, University of Granada, Campus Universitario de Cartuja, s/n, 18071, Granada, Spain.ORCID http://orcid.org/0000-0003-0870-4195
Miguel Padial-MolinaDepartment of Oral Surgery and Implant Dentistry, School of Dentistry, University of Granada, Campus Universitario de Cartuja, s/n, 18071, Granada, Spain.ORCID http://orcid.org/0000-0001-6222-1341
Gustavo Avila-OrtizDepartment of Periodontics, University of Iowa College of Dentistry, Iowa City, IA, USA.ORCID http://orcid.org/0000-0002-5763-0201
Francisco O'ValleDepartment of Pathology and IBIMER, School of Medicine, University of Granada, Granada, Spain.ORCID http://orcid.org/0000-0001-9207-2287
Andrea RavidaDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-3029-8130
Andres CatenaDepartment of Experimental Psychology, School of Psychology, University of Granada, Granada, Spain.ORCID http://orcid.org/0000-0002-0775-5751
Universidad de Granada · ESUniversity of Iowa · USUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate if there is epidemiological evidence of an association between edentulism and cognitive decline beside that currently available from limited sample-sized case series and cross-sectional studies considering limited co-variables. MATERIALS AND

methodsData from two USA national health surveys [NHIS 2014-2017 and NHANES 2005-2018] were analyzed using multinomial logistic regression to study the impact of type of edentulism and number of remaining teeth on memory and concentration problems. Age, gender, socioeconomic status, education level, cardiovascular health index, body mass index, exercise, alcohol, smoking habits, and anxiety and depression were used as covariates.

resultsThe combined population sample was 102,291 individuals. Age, socioeconomic status, educational level, anxiety and depression levels, and edentulism showed the highest odds ratios for cognitive decline. Number of teeth present in the mouth was found to be a predictor of cognitive status. This association showed a gradient effect, so that the lower the number of teeth, the greater the risk of exhibiting cognitive decline.

conclusionsEdentulism was found among the higher ORs for cognitive impairment. CLINICAL RELEVANCE: Maintenance of functional teeth through the promotion of oral health may contribute to the preservation of memory/concentration and other essential cognitive functions. Thus, increasing and efficiently coordinating efforts aimed at preventing of tooth loss in the adult population could substantially contribute to reduce the incidence of cognitive impairment.

Indexed as

Tooth LossAdultCognitionCross-Sectional StudiesHumansNutrition SurveysOral HealthAgingCognitive dysfunctionDementiaDental prosthesisMasticationOral health

Identifiers

PMID34881401
PMCPMC8979879
OpenAlexW4200594542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.