Evidence map›Paper›PMID 34881274›Full record

ReviewFrontiers in medicine2021

The Role of Exosomes in Viral Hepatitis and Its Associated Liver Diseases.

Hao Zhou, Zhi-Han Yan, Yuan Yuan, Chen Xing, Nan Jiang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Frontiers in cellular neuroscience · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Hao ZhouAffiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhi-Han YanDepartment of Hepatology, Wuxi Fifth People's Hospital, Wuxi, China.
Yuan YuanAffiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Chen XingDepartment of Oncology, The Second People's Hospital of Yancheng City, Yancheng, China.
Nan JiangDepartment of Urology, People's Hospital of Dongtai City, Dongtai, China.
Second Affiliated Hospital of Zhejiang University · CNWuxi People's Hospital · CNXingtai People's Hospital · CNYancheng Second People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes, the important carriers between cells, can carry proteins, micro ribonucleic acids (miRNAs), long non-coding RNAs (lncRNAs) and other molecules to mediate cellular information transduction. They also play an important role in the pathogenesis, prognosis and treatment of viral hepatitis and its associated liver diseases. Several studies have reported that viral hepatitis and its associated liver diseases, including hepatitis A, B, C and E; hepatic fibrosis and hepatocellular carcinoma, were closely associated with exosomes. Exploring the role of exosomes in viral hepatitis and associated liver diseases will enhance our understanding of these diseases. Therefore, this review mainly summarised the role of exosomes in viral hepatitis and its associated liver diseases to identify new strategies for liver diseases in clinical practise.

Indexed as

biomarkersexosomesfibrosishepatocellular carcinoma (HCC)therapeutic targetsviral hepatitis

Identifiers

PMID34881274
PMCPMC8645545
OpenAlexW3215260696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.