Evidence map›Paper›PMID 34881263›Full record

ReviewFrontiers in medicine2021

Persistence of Symptoms After Discharge of Patients Hospitalized Due to COVID-19.

Lili Wu, Yongxin Wu, Haiyan Xiong, Biqi Mei, Tianhui You

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Long-term Effects of COVID-19 on Sleep PatternsThoracic research and practice · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Long COVID and rheumatology: Clinical, diagnostic, and therapeutic implications.Best practice & research. Clinical rheumatology · 2022
    Review
  11. Article
  12. Review
  13. Global Trends and Research Hotspots in Long COVID: A Bibliometric Analysis.International journal of environmental research and public health · 2022
    Article
  14. Article
  15. Cytokine Profiles Associated With Acute COVID-19 and Long COVID-19 Syndrome.Frontiers in cellular and infection microbiology · 2022
    Article
  16. Article
  17. Long-COVID-19 clinical and health outcomes: an umbrella review.Therapeutic advances in infectious disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lili WuNursing Department, People's Hospital of Longhua, Shenzhen, China.
Yongxin WuSchool of Nursing, Guangdong Pharmaceutical University, Guangzhou, China.
Haiyan XiongNursing Department, People's Hospital of Longhua, Shenzhen, China.
Biqi MeiSchool of Nursing, Guangdong Pharmaceutical University, Guangzhou, China.
Tianhui YouSchool of Nursing, Guangdong Pharmaceutical University, Guangzhou, China.
Guangdong Pharmaceutical University · CNShenZhen People’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many patients who had coronavirus disease 2019 (COVID-19) had at least one symptom that persisted after recovery from the acute phase. Our purpose was to review the empirical evidence on symptom prevalence, complications, and management of patients with long COVID. We systematically reviewed the literature on the clinical manifestations of long COVID-19, defined by the persistence of symptoms beyond the acute phase of infection. Bibliographic searches in PubMed and Google Scholar were conducted to retrieve relevant studies on confirmed patients with long COVID that were published prior to August 30, 2021. The most common persistent symptoms were fatigue, cough, dyspnea, chest pains, chest tightness, joint pain, muscle pain, loss of taste or smell, hair loss, sleep difficulties, anxiety, and depression. Some of the less common persistent symptoms were skin rash, decreased appetite, sweating, inability to concentrate, and memory lapses. In addition to these general symptoms, some patients experienced dysfunctions of specific organs, mainly the lungs, heart, kidneys, and nervous system. A comprehensive understanding of the persistent clinical manifestations of COVID-19 can improve and facilitate patient management and referrals. Prompt rehabilitative care and targeted interventions of these patients may improve their recovery from physical, immune, and mental health symptoms.

Indexed as

COVID-19long-term effectpatient dischargereviewSARS-CoV-2

Identifiers

PMID34881263
PMCPMC8645792
OpenAlexW3215158902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.