Evidence map›Paper›PMID 34881261›Full record

ReviewFrontiers in medicine2021

Cell Therapy: Types, Regulation, and Clinical Benefits.

Abed El-Hakim El-Kadiry, Moutih Rafei, Riam Shammaa

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 5 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 5 syntheses or guidelines pooled it, 222 citations in OpenAlex.

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  11. Adoptive T-cell therapies in the clinic.Bioengineering & translational medicine · 2026
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59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Abed El-Hakim El-KadiryLaboratory of Thrombosis and Hemostasis, Montreal Heart Institute, Research Center, Montreal, QC, Canada.
Moutih RafeiDepartment of Pharmacology and Physiology, Université de Montréal, Montreal, QC, Canada.
Riam ShammaaCanadian Centre for Regenerative Therapy, Toronto, ON, Canada.
McGill University · CAUniversité de Montréal · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell therapy practices date back to the 19

Indexed as

bone marrow aspirate concentrate (BMAC)cancercell therapyFDA regulationsimmune diseasesmesenchymal stem cellsmulticellular therapiesregenerative medicine

Identifiers

PMID34881261
PMCPMC8645794
OpenAlexW3215765083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.