Evidence map›Paper›PMID 34881247›Full record

ArticleFrontiers in cell and developmental biology2021

Multiple Connection Pattern Combination From Single-Mode Data for Mild Cognitive Impairment Identification.

Weikai Li, Xiaowen Xu, Zhengxia Wang, Liling Peng, Peijun Wang, Xin Gao

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Weikai LiSchool of Information Science and Engineering, Chongqing Jiaotong University, Chongqing, China.
Xiaowen XuDepartment of Medical Imaging, Tongji Hospital, Shanghai, China.
Zhengxia WangSchool of Computer Science and Cyberspace Security, Hainan University, Hainan, China.
Liling PengShanghai Universal Medical Imaging Diagnostic Center, Shanghai, China.
Peijun WangDepartment of Medical Imaging, Tongji Hospital, Shanghai, China.
Xin GaoShanghai Universal Medical Imaging Diagnostic Center, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild cognitive impairment (MCI) is generally considered to be a key indicator for predicting the early progression of Alzheimer's disease (AD). Currently, the brain connection (BC) estimated by fMRI data has been validated to be an effective diagnostic biomarker for MCI. Existing studies mainly focused on the single connection pattern for the neuro-disease diagnosis. Thus, such approaches are commonly insufficient to reveal the underlying changes between groups of MCI patients and normal controls (NCs), thereby limiting their performance. In this context, the information associated with multiple patterns (e.g., functional connectivity or effective connectivity) from single-mode data are considered for the MCI diagnosis. In this paper, we provide a novel multiple connection pattern combination (MCPC) approach to combine different patterns based on the kernel combination trick to identify MCI from NCs. In particular, sixty-three MCI cases and sixty-four NC cases from the ADNI dataset are conducted for the validation of the proposed MCPC method. The proposed method achieves 87.40% classification accuracy and significantly outperforms methods that use a single pattern.

Indexed as

effective connectivityfunctional connectivitymild cognitive impairmentmultimodalmultiview

Identifiers

PMID34881247
PMCPMC8645991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.