Evidence map›Paper›PMID 34881179›Full record

ArticleFrontiers in oncology2021

Positive Reciprocal Feedback of

Yan Jin, Zhengming Zhang, Qiao Yu, Zhu Zeng, Hong Song, Xiaoxu Huang, Qi Kong, Hao Hu, Yabin Xia

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. LncRNA-Histone Modification Crosstalk: Orchestrating Cancer Pathobiology.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Review
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  10. The lactate metabolism and protein lactylation in epilepsy.Frontiers in cellular neuroscience · 2024
    Review
  11. Review
  12. Review
  13. Natural antisense transcripts as drug targets.Frontiers in molecular biosciences · 2022
    Review
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yan JinDepartment of Gastrointestinal Surgery, The First Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, China.
Zhengming ZhangDepartment of Gastrointestinal Surgery, The First Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, China.
Qiao YuDepartment of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhu ZengDepartment of Emergency Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hong SongDepartment of Pathology, The First Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, China.
Xiaoxu HuangDepartment of Gastrointestinal Surgery, The First Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, China.
Qi KongDepartment of Gastrointestinal Surgery, The First Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, China.
Hao HuDepartment of Gastrointestinal Surgery, The First Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, China.
Yabin XiaDepartment of Gastrointestinal Surgery, The First Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, China.
First Affiliated Hospital of Wannan Medical College · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany studies have reported the roles of the extracellular hypoxia microenvironment in the tumorigenesis and metastasis of multiple cancers. However, long noncoding RNAs (

methodsIn PC cells, the expression levels of

resultsRNA-seq revealed that

conclusionsOur results emphasized that the positive reciprocal loop of

Indexed as

HIF-1αhypoxialncRNA-ZEB1-AS1metastasispancreatic cancerZeb1

Identifiers

PMID34881179
PMCPMC8645903
OpenAlexW3215578395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.