Evidence map›Paper›PMID 34881164›Full record

Article3 Biotech2021

Tyrosine kinase nonreceptor 1 (TNK1) knockdown ameliorates hemorrhage shock-induced kidney injury via inhibiting macrophage M1 polarization.

Miaolong Tang, Jimin Cai, Yan Wang, Zhirong Huan, Hao Yao, Ce Xu, Xin Ge, Sheng Song

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Miaolong Tang *Department of Clinical Laboratory, Wuxi 9th Affiliated Hospital of Soochow University, Wuxi, 214000 Jiangsu People's Republic of China.
Jimin Cai *Department of ICU, Wuxi 9th Affiliated Hospital of Soochow University, Wuxi, 214000 Jiangsu People's Republic of China.
Yan WangDepartment of ICU, Wuxi 9th Affiliated Hospital of Soochow University, Wuxi, 214000 Jiangsu People's Republic of China.
Zhirong HuanDepartment of ICU, Wuxi 9th Affiliated Hospital of Soochow University, Wuxi, 214000 Jiangsu People's Republic of China.
Hao YaoDepartment of ICU, Wuxi 9th Affiliated Hospital of Soochow University, Wuxi, 214000 Jiangsu People's Republic of China.
Ce XuDepartment of ICU, Wuxi 9th Affiliated Hospital of Soochow University, Wuxi, 214000 Jiangsu People's Republic of China.
Xin GeDepartment of ICU, Wuxi 9th Affiliated Hospital of Soochow University, Wuxi, 214000 Jiangsu People's Republic of China.ORCID 0000-0003-1377-100X
Sheng SongDepartment of Spine Surgery, Wuxi 9th Affiliated Hospital of Soochow University, Wuxi, 214000 Jiangsu People's Republic of China.
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemorrhage shock (HS) is a major threat to patients with trauma and spontaneous bleeding, resulting in multi-organ failure including the kidney. Tyrosine kinase nonreceptor 1 (TNK1) has been shown to be upregulated in the kidney of experimental HS and patients with severe trauma

Indexed as

Hemorrhage shock (HS)InflammationMacrophage M1 polarizationTyrosine kinase nonreceptor 1 (TNK1)

Identifiers

PMID34881164
PMCPMC8599570
OpenAlexW3212774544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.