ReviewAging and disease2021
Depression and Dementia in Older Adults: A Neuropsychological Review.
Review in Aging and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
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Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Association Between Caregiver Psychosocial Factors and Depressive Symptoms in People With Dementia: A Systematic Review and Meta-Analysis.Journal of advanced nursing · 2026Pooled it
- Effects of different types of mind-body exercises on depressive symptoms in older adults: a systematic review and network meta-analysis.Frontiers in public health · 2026Pooled it
- My patient might be depressed - can I still screen for MCI? Exploring cognitive performance on the MoCA in older people screened for depressive symptoms with the PHQ-9.BMC geriatrics · 2025Trial
- Mayonnaise intake and depression: dose-response in humans and neurobehavioral and molecular mechanisms in zebrafish.Biochemistry and biophysics reports · 2026Article
- Worry and Anxiety in the Era of Early Diagnosis and Disease Modifying Treatment for Alzheimer's Disease.Current psychiatry reports · 2026Review
- Amino-Acid-Derived Androgen Receptor Modulators.ACS medicinal chemistry letters · 2026Article
- Cognitive Impairment, Dementia and Depression in Older Adults.Journal of clinical medicine · 2026Review
- MDMA-Assisted Treatment for PTSD, Anxiety, and Depression: A Visualized Literature Analysis over 30 Years.Current medicinal chemistry · 2026Review
- Socioeconomic disparities and nutritional aging: how food insecurity and financial hardship accelerate health decline in older adults.Frontiers in nutrition · 2026Review
- Depressive symptoms in hospitalized geriatric patients with and without cognitive impairment: a cross-sectional network analysis approach.Frontiers in medicine · 2026Article
- Integrated approaches to geriatric mental disorders: pathophysiology, interventions, and precision medicine horizons.Frontiers in psychiatry · 2026Review
- A brief checklist of modifiable dementia risk factors (RF12): associations with cognitive and affective measures in an Italian cohort.Frontiers in aging neuroscience · 2026Article
- Depression and clinical functioning among cognitively normal and mildly impaired older adults.Aging clinical and experimental research · 2025Article
- Beyond silence: Addressing mental health challenges and hopeful pathways for older adults.World journal of psychiatry · 2025Article
- Association between higher cerebrospinal fluid levels of phosphorylated tau and reduced depressive symptoms in patients with cognitive decline.PCN reports : psychiatry and clinical neurosciences · 2025Article
- Anticholinergics, executive function, and cognitive/behavioral changes in Down syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Association Between Physical Activity and the Risk of Dementia Among Patients With Depression: A Nationwide Cohort Study.Psychiatry investigation · 2025Article
- Current Methods in Clinical Alzheimer's Disease Research and Diagnosis.Molecular diagnosis & therapy · 2025Review
- Longitudinal associations of depression and diabetes with Alzheimer's disease and related dementias risk among American Indian and Alaska Native peoples.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Exploring Non-Pharmacologic Adjunctive Therapies for Patients with Neurodegenerative Diseases.Medicina (Kaunas, Lithuania) · 2025Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression and dementia are the most common neuropsychiatric disorders in the older adult population. There are a certain number of depressed patients who visit outpatient clinics because they suspect dementia due to similarities in the clinical symptoms in both disorders. Depressive symptoms associated with dementia may be diagnosed with depression, and treatment with antidepressants is continued for a long time. Depression and dementia differ in their treatment approaches and subsequent courses, and it is necessary to carefully differentiate between the two in the clinical practice of dementia treatment. In this review, I describe the similarities between depression and dementia and how to differentiate depression in dementia treatment based on the differences and emphasize that there is a significant potential to cure depression, in contrast to dementia, for which there is currently no fundamental therapy. Therefore, it is important to recognize that depression and dementia may present with common symptoms and to appropriately differentiate depressed patients who are suspected of having dementia. Dementia is a disorder in which cognitive dysfunction is caused by a variety of causative diseases and conditions, resulting in impairment of activities of daily living. However, current medical science has had difficulty finding a cure for the causative disease. Based on clinical findings, it has also been shown that the degree of symptoms for preexisting psychiatric disorders is alleviated as the brain ages. In the presence of dementia, the speed of the alleviation will increase. The importance of focusing on the positive aspects of aging is also discussed.
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