Evidence map›Paper›PMID 34881055›Full record

ArticleBiochemistry research international2021

Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer's Disease Mutations.

Alejandro Soto-Ospina, Pedronel Araque Marín, Gabriel de Jesús Bedoya, Andrés Villegas Lanau

Open access · goldAbstract read
In one paragraph

Article in Biochemistry research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Polyoxometalates bind multiple targets involved in Alzheimer's disease.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alejandro Soto-OspinaUniversity of Antioquia, Faculty of Medicine, Group Molecular Genetics, Medellín, Colombia.ORCID https://orcid.org/0000-0003-2382-7038
Pedronel Araque MarínEIA University, School of Life Sciences, Research and Innovation in Chemistry Formulations Group, Envigado, Colombia.
Gabriel de Jesús BedoyaUniversity of Antioquia, Faculty of Medicine, Group Molecular Genetics, Medellín, Colombia.
Andrés Villegas LanauUniversity of Antioquia, Faculty of Medicine, Group Molecular Genetics, Medellín, Colombia.ORCID https://orcid.org/0000-0003-1971-4364
Universidad de Antioquia · COEIA University · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease manifests itself in brain tissue by neuronal death, due to aggregation of

Identifiers

PMID34881055
PMCPMC8648483
OpenAlexW3215577349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.