Evidence map›Paper›PMID 34880994›Full record

ArticleChemical science2021

Plasticizer and catalyst co-functionalized PEDOT:PSS enables stretchable electrochemical sensing of living cells.

Jing Yan, Yu Qin, Wen-Ting Fan, Wen-Tao Wu, Song-Wei Lv, Li-Ping Yan, Yan-Ling Liu, Wei-Hua Huang

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Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Jing YanCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China yanlingliu@whu.edu.cn whhuang@whu.edu.cn.
Yu QinCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China yanlingliu@whu.edu.cn whhuang@whu.edu.cn.
Wen-Ting FanCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China yanlingliu@whu.edu.cn whhuang@whu.edu.cn.
Wen-Tao WuCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China yanlingliu@whu.edu.cn whhuang@whu.edu.cn.
Song-Wei LvSchool of Pharmacy, Changzhou University Changzhou 213164 China.
Li-Ping YanCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China yanlingliu@whu.edu.cn whhuang@whu.edu.cn.
Yan-Ling LiuCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China yanlingliu@whu.edu.cn whhuang@whu.edu.cn.ORCID https://orcid.org/0000-0002-7386-354X
Wei-Hua HuangCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China yanlingliu@whu.edu.cn whhuang@whu.edu.cn.ORCID https://orcid.org/0000-0001-8951-075X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, stretchable electrochemical sensors have stood out as a powerful tool for the detection of soft cells and tissues, since they could perfectly comply with the deformation of living organisms and synchronously monitor mechanically evoked biomolecule release. However, existing strategies for the fabrication of stretchable electrochemical sensors still face with huge challenges due to scarce electrode materials, demanding processing techniques and great complexity in further functionalization. Herein, we report a novel and facile strategy for one-step preparation of stretchable electrochemical biosensors by doping ionic liquid and catalyst into a conductive polymer (poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate), PEDOT:PSS). Bis(trifluoromethane) sulfonimide lithium salt as a small-molecule plasticizer can significantly improve the stretchability and conductivity of the PEDOT:PSS film, and cobalt phthalocyanine as an electrocatalyst endows the film with excellent electrochemical sensing performance. Moreover, the functionalized PEDOT:PSS retained good cell biocompatibility with two extra dopants. These satisfactory properties allowed the real-time monitoring of stretch-induced transient hydrogen peroxide release from cells. This work presents a versatile strategy to fabricate conductive polymer-based stretchable electrodes with easy processing and excellent performance, which benefits the in-depth exploration of sophisticated life activities by electrochemical sensing.

Identifiers

PMID34880994
PMCPMC8580016

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.