Evidence map›Paper›PMID 34880985›Full record

ArticleChemical science2021

An erythrocyte-delivered photoactivatable oxaliplatin nanoprodrug for enhanced antitumor efficacy and immune response.

Na Wang, Zhiqin Deng, Qi Zhu, Jianxiong Zhao, Kai Xie, Peng Shi, Zhigang Wang, Xianfeng Chen, Feng Wang, Jiahai Shi and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Red blood cells: a potential delivery system.Journal of nanobiotechnology · 2023
    Review
  10. Recent Advances in Light-Controlled Activation of Pt(IV) Prodrugs.International journal of molecular sciences · 2022
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Na WangDepartment of Chemistry, City University of Hong Kong Hong Kong SAR P. R. China guangzhu@cityu.edu.hk.
Zhiqin DengDepartment of Chemistry, City University of Hong Kong Hong Kong SAR P. R. China guangzhu@cityu.edu.hk.ORCID https://orcid.org/0000-0002-2852-2009
Qi ZhuDepartment of Materials Science and Engineering, City University of Hong Kong Hong Kong SAR P. R. China.
Jianxiong ZhaoDepartment of Materials Science and Engineering, City University of Hong Kong Hong Kong SAR P. R. China.
Kai XieDepartment of Biomedical Engineering, City University of Hong Kong Hong Kong SAR P. R. China.
Peng ShiDepartment of Biomedical Engineering, City University of Hong Kong Hong Kong SAR P. R. China.ORCID https://orcid.org/0000-0003-0629-4161
Zhigang WangSchool of Pharmaceutical Sciences, Health Science Center, Shenzhen University Shenzhen 518060 P. R. China.
Xianfeng ChenSchool of Engineering, Institute for Bioengineering, The University of Edinburgh Mayfield Road Edinburgh EH9 3JL UK.ORCID https://orcid.org/0000-0002-3189-2756
Feng WangDepartment of Materials Science and Engineering, City University of Hong Kong Hong Kong SAR P. R. China.ORCID https://orcid.org/0000-0001-9471-4386
Jiahai ShiDepartment of Biomedical Sciences, City University of Hong Kong Hong Kong SAR P. R. China.ORCID https://orcid.org/0000-0002-6467-8289
Guangyu ZhuDepartment of Chemistry, City University of Hong Kong Hong Kong SAR P. R. China guangzhu@cityu.edu.hk.ORCID https://orcid.org/0000-0002-4710-7070
City University of Hong Kong · HKShenzhen University Health Science Center · CNUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outcome of conventional platinum (Pt)-based chemotherapy is limited by reduced circulation, failure to accumulate in the tumor, and dose-limiting toxicity arising from non-controllable activation. To address these limitations, we present an erythrocyte-delivered and near-infrared (NIR) photoactivatable Pt

Identifiers

PMID34880985
PMCPMC8580000
OpenAlexW3204535357

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.