Evidence map›Paper›PMID 34880970›Full record

ArticleDermatology reports2021

Paraneoplastic dermatomyositis and prostate cancer: Myopathy regression under cancer-directed therapy.

Mafalda Miranda Baleiras, Luís Maduro, Carolina Vasques, Filipa Ferreira, Marta Mesquita Pinto, Ana Martins

Open access · goldAbstract read
In one paragraph

Article in Dermatology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mafalda Miranda BaleirasHospital São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Portugal.
Luís MaduroHospital São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Portugal.
Carolina VasquesHospital São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Portugal.
Filipa FerreiraHospital São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Portugal.
Marta Mesquita PintoHospital São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Portugal.
Ana MartinsHospital São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Portugal.
Centro Hospitalar de Lisboa Ocidental · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the second most frequent malignancy in men worldwide and the fifth leading cause of death. Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy characterized by musculocutaneous manifestations. However, DM can also present as a paraneoplastic syndrome of an underlying neoplasm. We report a case of a 65-year-old man diagnosed with prostate adenocarcinoma in the setting of severe dysphagia, muscle weakness and a facial erythematous rash. At first, the DM-related symptoms resolved with the initial treatment for the underlying malignancy. Yet, they flared up as the tumor progressed. To sum up, DM is a rare systemic disorder with unknown etiology. There is a well-established association between DM and malignancy. Malignancy-headed therapy can improve DM manifestations and the recurrence of DM symptoms may act as an early warning of malignancy relapse.

Indexed as

DermatomyositisMyositis- Specific AntibodyParaneoplastic SyndromeProstate CancerRecurrence

Identifiers

PMID34880970
PMCPMC8611514
OpenAlexW3192337023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.