Evidence map›Paper›PMID 34880952›Full record

ArticleJournal of infection prevention2021

Lack of regulation over antibiotic prescription and dispensation: A prospective cohort in a community setting.

Jacques Choucair, Elie Haddad, Gebrael Saliba, Nabil Chehata, Jennifer Makhoul

Abstract read
In one paragraph

Article in Journal of infection prevention, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jacques ChoucairDepartment of Infectious Diseases, Saint Joseph University, Faculty of Medicine, Beirut, Lebanon.
Elie HaddadDepartment of Infectious Diseases, Saint Joseph University, Faculty of Medicine, Beirut, Lebanon.
Gebrael SalibaDepartment of Infectious Diseases, Saint Joseph University, Faculty of Medicine, Beirut, Lebanon.
Nabil ChehataDepartment of Infectious Diseases, Saint Joseph University, Faculty of Medicine, Beirut, Lebanon.
Jennifer MakhoulDepartment of Infectious Diseases, Saint Joseph University, Faculty of Medicine, Beirut, Lebanon.ORCID https://orcid.org/0000-0002-8493-5713

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe emergence of bacterial resistance caused health authorities to attempt to implement strict regulations for rational antibiotic prescription. However, supervision is often neglected in low- and middle-income countries, leading to inappropriate administration of antibiotics. The objective of our study is to highlight the lack of monitoring in the community setting of a middle-income country. MATERIAL AND

methodsWe asked 68 patients presenting to an infectious diseases consultation office to report the antibiotic courses they had taken in the three months preceding their visit. We assessed for treatment indication, molecule choice, dosing and duration, as well as microbial cultures, demographics and specialty of the prescriber.

resultsAmong the 68 patients included in our study, we counted a total of 95 outpatient antibiotic courses, mostly composed of quinolones (36%), followed by amoxicillin-clavulanate (21%). The prescriber was most commonly a primary care physician, but we reported several cases of auto-medication and dispensation of antibiotics by pharmacists. Only 30% of cases had true indications for antibiotics.

conclusionIn sum, our results indicate an evident lack of regulation over the administration of antibiotics. This easy accessibility needs to be promptly addressed as we run the risk of inevitable bacterial resistance.

Indexed as

Antibioticsbacterial resistanceinfectious diseasesover-the-counterprescription

Identifiers

PMID34880952
PMCPMC8647644

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.