ArticleFrontiers in endocrinology2021
Ovarian Endometrioma Negatively Impacts Oocyte Quality and Quantity But Not Pregnancy Outcomes in Women Undergoing IVF/ICSI Treatment: A Retrospective Cohort Study.
Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Association between endometriosis and adverse reproductive and perinatal outcomes in women undergoing assisted reproductive technology: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Endometriosis as a risk factor: impact on IVF outcomes and reproductive parameters: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2025Pooled it
- Reducing Photo-Oxidative Stress in IVF: A Retrospective Analysis of Cycles with Poor Blastocyst Development.Journal of clinical medicine · 2026Article
- Evaluation of the use of dienogest in women with deep endometriosis and ovarian endometrioma: a retrospective cohort study.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Development and External Validation of Machine Learning Model to Predict Live Birth Following Assisted Reproductive Technology in Women with Ovarian Endometriomas: A Decision-Support Tool.Clinical epidemiology · 2026Article
- Identifying key determinants of cumulative live birth in women with ovarian endometrioma undergoing ethanol sclerotherapy followed byFrontiers in cell and developmental biology · 2026Article
- Analysis of risk factors compromising embryo quality and quantity in patients with endometriosis.Frontiers in medicine · 2026Article
- Determining factors associated with the number of oocytes with appropriate morphology in infertile women: A cross-sectional study.International journal of reproductive biomedicine · 2025Article
- Should patients undergo endometrioma surgery before IVF/ICSI? a retrospective study with propensity score matching.Reproductive health · 2025Article
- Iron-responsive ZNF185 overexpression drives mitochondrial fission and endoplasmic reticulum stress via cytoskeletal remodeling in granulosa cells.Cell death discovery · 2025Article
- The impact of surgical intervention on time to conception and obstetric outcomes in women with endometriomas: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- Ovarian Tissue Removed with Endometrioma May Reflect the Quality of the Adjacent Ovary.Healthcare (Basel, Switzerland) · 2025Article
- The Effects of Endometriosis on Oocyte and Embryo Quality.Journal of clinical medicine · 2025Review
- Single-cell dual-omics reveals translational and transcriptional landscapes and regulations in oocytes from ovarian endometriosis patients.Frontiers in endocrinology · 2025Article
- The Effect of Endometriosis on In Vitro Fertilization Outcomes: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2024Review
- Association between follicular fluid bacteria with inflammatory markers of the complete blood count and the outcomes of assisted reproductive technology in women with endometriosis: A case-control study.Health science reports · 2024Article
- Article
- Ovarian Stimulation for In Vitro Fertilization and Reproductive Outcome after Surgical Treatment of Endometriosis Compared with Tubal Factor Infertility.Clinics and practice · 2023Article
- Development and validation of a nomogram model for predicting clinical pregnancy in endometriosis patients undergoing fresh embryo transfer.BMC pregnancy and childbirth · 2023Article
- Surgical Management of Ovarian Endometrioma: Impact on Ovarian Reserve Parameters and Reproductive Outcomes.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To determine the impact of ovarian endometrioma Methods: This retrospective study was conducted using two groups. The endometrioma group consisted of 862 women with infertility who had ovarian endometriomas and underwent their first ovarian stimulation for IVF/ICSI treatment between January 2011 to December 2019 at a public university hospital. A non-endometrioma comparison group, comprising 862 women with other infertility factors, was matched according to maternal age, body mass index (BMI), and infertility duration. Ovarian reserve and response and IVF/ICSI and pregnancy outcomes between the two groups were analyzed. Multivariate logistic regression (MLR) analysis was conducted on the basis of clinical covariates assessed for their association with live birth. Results: The results showed that significantly lower antral follicle count (AFC), anti-Müllerian hormone (AMH), ovarian sensitivity index (OSI), oocyte maturation and fertilization rates, blastocyst rate, number of oocytes retrieved, and available embryos were found in women with endometrioma compared with the control, respectively (P < 0.05). The cumulative live birth rate Conclusions: The data from this study supported the conclusion that ovarian endometrioma negatively impacts oocyte quality and quantity, but not overall pregnancy outcomes, in women undergoing IVF/ICSI treatment. Endometrioma lowers the cumulative live birth rate by decreasing the number of embryos. Surgical excision of endometrioma prior to IVF/ICSI can partly improve oocyte maturation and fertilization rates but not pregnancy outcomes.
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