Evidence map›Paper›PMID 34880830›Full record

ReviewFrontiers in endocrinology2021

Apelin and Vasopressin: The Yin and Yang of Water Balance.

Pierre-Emmanuel Girault-Sotias, Romain Gerbier, Adrien Flahault, Nadia de Mota, Catherine Llorens-Cortes

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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  5. Syndrome of Inappropriate Antidiuresis.Journal of the American Society of Nephrology : JASN · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Pierre-Emmanuel Girault-SotiasLaboratory of Central Neuropeptides in the Regulation of Body Fluid Homeostasis and Cardiovascular Functions, Center for Interdisciplinary Research in Biology (CIRB), French National Institute for Health and Medical Research (INSERM), Unit U1050, National Center for Scientific Research (CNRS), Mixed Research Unit 7241, College de France, Paris, France.
Romain GerbierLaboratory of Central Neuropeptides in the Regulation of Body Fluid Homeostasis and Cardiovascular Functions, Center for Interdisciplinary Research in Biology (CIRB), French National Institute for Health and Medical Research (INSERM), Unit U1050, National Center for Scientific Research (CNRS), Mixed Research Unit 7241, College de France, Paris, France.
Adrien FlahaultLaboratory of Central Neuropeptides in the Regulation of Body Fluid Homeostasis and Cardiovascular Functions, Center for Interdisciplinary Research in Biology (CIRB), French National Institute for Health and Medical Research (INSERM), Unit U1050, National Center for Scientific Research (CNRS), Mixed Research Unit 7241, College de France, Paris, France.
Nadia de MotaLaboratory of Central Neuropeptides in the Regulation of Body Fluid Homeostasis and Cardiovascular Functions, Center for Interdisciplinary Research in Biology (CIRB), French National Institute for Health and Medical Research (INSERM), Unit U1050, National Center for Scientific Research (CNRS), Mixed Research Unit 7241, College de France, Paris, France.
Catherine Llorens-CortesLaboratory of Central Neuropeptides in the Regulation of Body Fluid Homeostasis and Cardiovascular Functions, Center for Interdisciplinary Research in Biology (CIRB), French National Institute for Health and Medical Research (INSERM), Unit U1050, National Center for Scientific Research (CNRS), Mixed Research Unit 7241, College de France, Paris, France.
Collège de France · FRCentre Interdisciplinaire de Recherche en Biologie · FRCentre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apelin, a (neuro)vasoactive peptide, plays a prominent role in controlling body fluid homeostasis and cardiovascular functions. Experimental data performed in rodents have shown that apelin has an aquaretic effect

Indexed as

ApelinApelin ReceptorsBrainHumansNeuronsVasopressinsWater-Electrolyte BalanceApelinApelin ReceptorsVasopressinsapelinapelin receptordiuresishyponatremiametabolically stable apelin-17 analogsosmolalityvasopressin

Identifiers

PMID34880830
PMCPMC8645901
OpenAlexW3217648196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.