Evidence map›Paper›PMID 34880751›Full record

ArticleFrontiers in pharmacology2021

Cinacalcet Targets the Neurokinin-1 Receptor and Inhibits PKCδ/ERK/P65 Signaling to Alleviate Dextran Sulfate Sodium-Induced Colitis.

Yuehong Chen, Huan Liu, Qiuping Zhang, Yubin Luo, Liang Wu, Yutong Zhong, Zhigang Tang, Yaoyu Pu, Chenyang Lu, Geng Yin and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. 7-azaindole as privileged scaffold: Advances in drug design and structural modification.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  2. Exploring multiple drug actions of a CaNaunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yuehong ChenDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Huan LiuDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Qiuping ZhangDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Yubin LuoDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Liang WuDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Yutong ZhongDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Zhigang TangDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Yaoyu PuDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Chenyang LuDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Geng YinDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Qibing XieDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cinacalcetinflammatory bowel diseaseneurokinin-1 receptorNF-κBtumor necrosis factor α

Identifiers

PMID34880751
PMCPMC8645985
OpenAlexW3215998488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.