Evidence map›Paper›PMID 34880734›Full record

ArticleFrontiers in systems neuroscience2021

Numerical Simulation: Fluctuation in Background Synaptic Activity Regulates Synaptic Plasticity.

Yuto Takeda, Katsuhiko Hata, Tokio Yamazaki, Masaki Kaneko, Osamu Yokoi, Chengta Tsai, Kazuo Umemura, Tetsuro Nikuni

Abstract read
In one paragraph

Article in Frontiers in systems neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuto TakedaDepartment of Physics, Tokyo University of Science, Tokyo, Japan.
Katsuhiko HataDepartment of Physics, Tokyo University of Science, Tokyo, Japan.
Tokio YamazakiDepartment of Physics, Tokyo University of Science, Tokyo, Japan.
Masaki KanekoKYB Medical Service Co., Ltd., Tokyo, Japan.
Osamu YokoiDepartment of Neuroscience, Research Center for Mathematical Medicine, Tokyo, Japan.
Chengta TsaiDepartment of Neuroscience, Research Center for Mathematical Medicine, Tokyo, Japan.
Kazuo UmemuraDepartment of Physics, Tokyo University of Science, Tokyo, Japan.
Tetsuro NikuniDepartment of Physics, Tokyo University of Science, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synaptic plasticity is vital for learning and memory in the brain. It consists of long-term potentiation (LTP) and long-term depression (LTD). Spike frequency is one of the major components of synaptic plasticity in the brain, a noisy environment. Recently, we mathematically analyzed the frequency-dependent synaptic plasticity (FDP)

Indexed as

background synaptic activitycalcium-based modelfluctuationfrequency-dependent synaptic plasticityneural noise

Identifiers

PMID34880734
PMCPMC8646040

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.